We investigate changes in human c-type lysozyme flexibility upon mutation via a Distance Constraint Model, which gives a statistical mechanical treatment of network rigid[...]

Proteins provide innumerable cellular functions and benefits for all kingdoms in the domains of life. Advancements in the high throughput collection and analysis of prot[...]

Echinoderms are highly regenerative animals that share a common ancestor with chordates, including humans. While the two phyla share a common ancestor, echinoderms defeat[...]

Gene prediction, a fundamental task in genomics, plays a pivotal role in decipheringthe functional elements of genomes. However, accurate gene prediction remains a challe[...]

Consumption of fruits and vegetables has been linked to a reduced risk of cancer and other chronic diseases, but the molecular mechanisms supporting these connections rem[...]

Metabolomics has emerged as an integral part of systems biology research that attempts to comprehensively study low molecular weight organic and inorganic metabolites und[...]

We applied a novel strategy to infer sequence circularity and complete assembly of four mitochondrial genomes (mitogenomes) of the frog families Bufonidae (Melanophrynisc[...]

At ground level, ozone is a pollutant that poses serious risk to both human health and crop yields. In addition to being a vital economic crop in the US and abroad, conv[...]

Antibodies are large, multi-chain proteins which play a critical roll in the func-tioning of vertebrate immune systems. Immune effector cells which are responsiblefor the[...]

Ovarian cancer is the most lethal gynecologic cancer in the United States. If caught in early stages, patient survival rate is 94%, late stage survival rates drop to 28%.[...]