The recent advance of single-cell technologies has provided an unprecedented opportunity to bring new insights into many complex biological phenomena, such as the regulat[...]

Although transcription is one of the most important biological functions of cells, our understanding of its regulation is still limited. In this dissertation, we have st[...]

The problem of bias resulting from biological and technological sources is one that must be consistently reexamined alongside the development of new technologies and meth[...]

Recent advancements in single-cell RNA sequencing have revolutionized our understanding of gene expression regulation under various biological contexts, providing higher [...]