DNA and RNA are structurally and functionally diverse biopolymers that haveshown promise in recent years as a powerful biomedical tool, in the form of nucleic acid nanote[...]

The growing interest in RNA biology, along with an expansion in computational capabilities, throughput, and sensitivity has provided researchers new tools to probe RNA. R[...]

Programmed interactions of nucleic acids—including DNA and RNA—orchestrate genetic expression and downstream cellular processes at every level. The structures of nucleic [...]

The human body operates using various stimuli-responsive mechanisms, dictating biological activity via reaction to external cues. Hydrogels are networked hydrophilic poly[...]

The human body operates using various stimuli-responsive mechanisms, dictating biological activity via reaction to external cues. Hydrogels are networked hydrophilic poly[...]

Nucleic acids (DNA and RNA) are ubiquitous biomolecules found throughout all living organisms. They can act as genetic information storage and messengers, enzymes, molecu[...]

The recent advance of single-cell technologies has provided an unprecedented opportunity to bring new insights into many complex biological phenomena, such as the regulat[...]

Although transcription is one of the most important biological functions of cells, our understanding of its regulation is still limited. In this dissertation, we have st[...]

The problem of bias resulting from biological and technological sources is one that must be consistently reexamined alongside the development of new technologies and meth[...]

Recent advancements in single-cell RNA sequencing have revolutionized our understanding of gene expression regulation under various biological contexts, providing higher [...]