Gene regulation networks (GRNs) are the bases for virtually all biological processes. To gain a global understanding of GRNs encoded in a genome, we first need to identif[...]

The importance of flexibility and stability on protein function has been recognized for over five decades. A protein must be flexible enough to mediate a reaction pathway[...]

Considering the ever growing world population as well as climate change, it has become essential to improve crops in order to reach higher yields, more tolerance to pests[...]

Although transcription is one of the most important biological functions of cells, our understanding of its regulation is still limited. In this dissertation, we have st[...]

ABSTRACT Burkholderia multivorans is an opportunistic pathogen that poses a health risk to patients with cystic fibrosis (CF). The use of broad-range antibiotics to comba[...]

There is currently a major gap in understanding the physiological processes of tissue grade animals from early diverging phyla, particularly within the context of the mol[...]

The field of paleoanthropology is tasked with studying the morphology of extinct hominins using fossilized remains. To study the evolution of the human brain, researchers[...]

Vesicular stomatitis virus (VSV) based oncolytic viruses are promising agents against various cancers. We have shown that pancreatic ductal adenocarcinoma (PDAC) cell lin[...]

Post-glacial interactions between climate, landscapes, and soils remain poorly understood, especially in alpine and sub-alpine areas. Here, I aim to increase understandin[...]

Soil development combined with sediment storage and erosion in small, upland watersheds are key landscape processes for which assumptions are frequently made but rarely v[...]