Search results | J. Murrey Atkins Library

Title: Z-DNA binding protein 1 mediates necroptotic and apoptotic cell death pathways in murine astrocytes following herpes simplex virus-1 infection
Author: Marriott, Ian, Jeffries, Austin M., Suptela, Alexander J.
Date Created: 2022
Subjects--Topical: Herpes simplex virus, DNA
Description: The mechanisms by which glia respond to viral central nervous system (CNS) pathogens are now becoming apparent with the demonstration that microglia and astrocytes express an array of pattern recognition receptors that include intracellular RNA an...

Title: Whole genome sequencing of Plasmodium vivax isolates reveals frequent sequence and structural polymorphisms in erythrocyte binding genes
Author: Janies, Daniel, Lo, Eugenia, Ford, Anthony, Kepple, Daniel
Date Created: 2020
Subjects--Topical: Communicable diseases, Malaria
Description: Plasmodium vivax malaria is much less common in Africa than the rest of the world because the parasite relies primarily on the Duffy antigen/chemokine receptor (DARC) to invade human erythrocytes, and the majority of Africans are Duffy negative. R...

Title: Venomix : a simple bioinformatic pipeline for identifying and characterizing toxin gene candidates from transcriptomic data
Author: Janies, Daniel, Reitzel, Adam M., Macrander, Jason
Date Created: 2018
Subjects--Topical: Genomics, Biology
Description: The advent of next-generation sequencing has resulted in transcriptome-based approaches to investigate functionally significant biological components in a variety of non-model organism. This has resulted in the area of venomics: a rapidly growing ...

Title: Using Nematostella vectensis to study the interactions between genome, epigenome, and bacteria in a changing environment
Author: Reitzel, Adam M., Fraune, Sebastian, Foret, Sylvain
Date Created: 2016
Subjects--Topical: Gene expression, Biology
Description: The phenotype of an animal cannot be explained entirely by its genes. It is now clear that factors other than the genome contribute to the ecology and evolution of animals. Two fundamentally important factors are the associated microbiota and epig...

Title: Twinkle twinkle brittle star : the draft genome of Ophioderma brevispinum (Echinodermata: Ophiuroidea) as a resource for regeneration research
Author: Janies, Daniel, Machado, Denis Jacob, Reid, Robert, Kofsky, Janice
Date Created: 2022
Subjects--Topical: Genomics, Biology
Description: Background Echinoderms are established models in experimental and developmental biology, however genomic resources are still lacking for many species. Here, we present the draft genome of Ophioderma brevispinum, an emerging model organism in the f...

Title: Transcriptome profiling of a beach-adapted wild legume for dissecting novel mechanisms of salinity tolerance
Author: Song, Bao-Hua, Zhang, Hengyou, Zuelsdorf, Christine, Penneys, Darin
Subjects--Topical: Plant ecology, Gene expression
Description: Strophostyles helvola is a close relative to common bean (Phaseolus vulgaris) and inhabits both coastal and non-coastal regions in North America. However, the mechanism of saline adaptation in S. helvola remains unclear. A transcriptome profiling ...

Title: Toll-like receptor-mediated recognition of nucleic acid nanoparticles (NANPs) in human primary blood cells
Author: Afonin, Kirill A., Truong, Nguyen, Halman, Justin
Date Created: 2019
Subjects--Topical: Nucleic acids, Chemistry
Description: Infusion reactions (IRs) create a translational hurdle for many novel therapeutics, including those utilizing nanotechnology. Nucleic acid nanoparticles (NANPs) are a novel class of therapeutics prepared by rational design of relatively short olig...

Title: Therapeutic immunomodulation by rationally designed nucleic acids and nucleic acid nanoparticles (NANPs)
Author: Panigaj, Martin, Skelly, Elizabeth, Beasock, Damian, Marriott, Ian
Date Created: 2023
Subjects--Topical: Immunology, Immune response--Regulation
Description: The immune system has evolved to defend organisms against exogenous threats such as viruses, bacteria, fungi, and parasites by distinguishing between self and non-self. In addition, it guards us against other diseases, such as cancer, by detecting...

Title: Therapeutic immunomodulation by rationally designed nucleic acids and nucleic acid nanoparticles
Author: Afonin, Kirill A., Marriott, Ian, Panigaj, Martin
Date Created: 2023
Subjects--Topical: Nucleic acids, Chemistry
Description: The immune system has evolved to defend organisms against exogenous threats such as viruses, bacteria, fungi, and parasites by distinguishing between self and non-self. In addition, it guards us against other diseases, such as cancer, by detecting...

Title: The immunorecognition, subcellular compartmentalization, and physicochemical properties of nucleic acid nanoparticles can be controlled by composition modification
Author: Johnson, M. Brittany, Halman, Justin, Marriott, Ian, Afonin, Kirill A., Miller, Daniel K., Cooper, Joseph S., Khisamutdinov, Emil F.
Subjects--Topical: Immunology, Nucleic acids, Nanoparticles
Description: Nucleic acid nanoparticles (NANPs) have become powerful new platforms as therapeutic and diagnostic tools due to the innate biological ability of nucleic acids to identify target molecules or silence genes involved in disease pathways. However, th...

Title: The immunorecognition, subcellular compartmentalization, and physicochemical properties of nucleic acid nanoparticles can be controlled by composition modification
Author: Afonin, Kirill A., Marriott, Ian, Halman, Justin
Date Created: 2020
Subjects--Topical: Nucleic acids, Chemistry
Description: Nucleic acid nanoparticles (NANPs) have become powerful new platforms as therapeutic and diagnostic tools due to the innate biological ability of nucleic acids to identify target molecules or silence genes involved in disease pathways. However, th...

Title: The immunological capacity of thrombocytes
Author: Ferdous, Farzana, Scott, Thomas
Date Created: 2023
Subjects--Topical: Immune response, Blood platelets
Description: Thrombocytes are numerous in the blood of aves (birds) and ichthyoids (fish). The origin of this cell type is a common hematopoietic stem cell giving rise to a cell that is active in blood coagulation, inflammatory functions, and the immune respon...

Title: The complete mitochondrial genome of the sea urchin, Echinometra sp. EZ
Author: Ketchum, Remi, DeBiasse, Melissa B., Ryan, Joseph F., Burt, John A., Reitzel, Adam M.
Subjects--Topical: Mitochondrial DNA, Sea urchins
Description: The complete mitogenome of Echinometra sp. EZ has been described and fully annotated in this study. Phylogenetic analysis of cytochrome c oxidase subunit I (COI) from six Echinometra species confirms that our sample is E. sp. EZ. The mitogenome is...

Title: Submicroscopic infection and G6PD deficiency in malaria patients
Author: Witherspoon, Logan, Witherspoon, Logan, Kepple, Daniel, Lo, Eugenia, Abagero, Beka
Date Created: 2022, 2022, 2022
Subjects--Topical: Malaria, Public health
Description: Plasmodium vivax malaria is a neglected tropical disease, despite being more geographically widespread than any other form of malaria. Glucose-6-phosphate dehydrogenase (G6PD) is a cytosolic enzyme with a vital role for the integrity and functioni...

Title: Some like it hot : population-specific adaptations in venom production to abiotic stressors in a widely distributed cnidarian
Author: Reitzel, Adam M., Sachkova, Maria Y., Macrander, Jason, Surm, Joachim M., Aharoni, Reuven, Menard-Harvey, Shelcie S., Klock, Amy, Leach, Whitney, Moran, Yehu
Subjects--Topical: Predation (Biology), Venom
Description: Background In cnidarians, antagonistic interactions with predators and prey are mediated by their venom, whose synthesis may be metabolically expensive. The potentially high cost of venom production has been hypothesized to drive population-specif...

Title: Sex-specific and developmental expression of dmrt genes in the starlet sea anemone, Nematostella vectensis
Author: Reitzel, Adam M., Traylor-Knowles, Nikki G., Kane, Eric G.
Date Created: 2015
Subjects--Topical: Evolution (Biology), Biology
Description: Background: The molecular mechanisms underlying sex determination and differentiation in animals are incredibly diverse. The Dmrt (doublesex and mab-3 related transcription factor) gene family is an evolutionary ancient group of transcription fact...

Title: Separating features from functionality : a computational analysis of vaccination apps
Author: Shaw, George, Nadkarni, Devaki, Phann, Eric, Sielaty, Rachel Ashby
Date Created: 2022
Subjects--Topical: Mobile apps, Public health
Description: Some latest estimates show that approximately 95% of Americans own a smartphone with numerous functions such as SMS text messaging, the ability to take high-resolution pictures, and mobile software apps. Mobile health apps focusing on vaccination ...

Title: Selection and utility of single nucleotide polymorphism markers to reveal fine-scale population structure in human malaria parasite Plasmodium falciparum
Author: Janies, Daniel, Lo, Eugenia, Ford, Anthony
Date Created: 2018
Subjects--Topical: Communicable diseases, Malaria
Description: Single nucleotide polymorphisms (SNPs) have been shown to be useful in revealing population structure with continental-and regional-scale samples. In epidemiological study, a careful selection of SNPs to track disease spread in local communities w...

Title: Salt tolerance response revealed by RNA-Seq in a diploid halophytic wild relative of sweet potato
Author: Loraine, Ann, Luo, Yan, Reid, Robert, Song, Bao-Hua
Date Created: 2017
Subjects--Topical: Genomics, Crop improvement
Description: Crop wild relatives harbor exotic and novel genetic resources, which hold great potential for crop improvement. Ipomoea imperati is a wild diploid relative of sweet potato with the capability of high salinity tolerance. We compared the transcripto...

Title: Revisiting the use of graph centrality models in biological pathway analysis
Author: Loraine, Ann, Mostafavi, M. Taghi, Yeganeh, Pourya Naderi, Richardson, Christine
Date Created: 2020
Subjects--Topical: Biological systems, Graph theory
Description: The use of graph theory models is widespread in biological pathway analyses as it is often desired to evaluate the position of genes and proteins in their interaction networks of the biological systems. In this article, we argue that the common st...