Small molecule fluorophores are critical for fluorescence spectroscopy, and enable the measurement of a wide array of biological processes and dynamics. For many biologic[...]

Vibrio vulnificus is ubiquitous in estuarine and coastal waters worldwide and associates naturally with a variety of aquatic organisms. Notably, it is a highly invasive h[...]

When introduced to harsh conditions such as low pH, pathogenic Escherichia coli can secrete colanic acid, an exopolysaccharide that completely engulfs the organism, to es[...]

This thesis investigates the model intrinsically disordered protein (IDP) κ-casein and the multidomain protein Sleeping Beauty (SB) transposase. Using advanced techniques[...]

In this work, the in vitro characterization profiles of delivery vehicles, specifically polyamidoamine (PAMAM) dendrimers, are assessed to investigate their impact on pre[...]

Nucleic acids are highly integrated into molecular biology and exhibit very interesting character. They have immense engineering potential to improve human health and inf[...]

Bacterial cell surface glycans mediate pathogenic and symbiotic interactions with hosts and other organisms. The implications of bacterial glycans in human health have ma[...]

Reversed-phase liquid chromatography (RPLC) of intact proteins induces conformational changes due to the denaturing effects of both the hydrophobic stationary phase and t[...]

Bordetella pertussis is a gram-negative bacterium that is the causative agent of whooping cough, a highly contagious disease that can be fatal in very young children. The[...]

Chronic diseases like cancer are characterized by complex interactions between multiple pathways leading to treatment resistance and invasiveness. Repeated cycles of cyto[...]