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A dv ances in affordable transcriptome sequencing combined with better exon and gene prediction has motivated many to compare transcription across the tree of lif e. W e [...]
2024 | articles |
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Freshwater Unionid bivalves have recently faced ecological upheaval through pollution, barriers to dispersal, harvesting, and changes in fish–host prevalence. Currently, [...]
2023 | articles |
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The genetic basis of phenotypic differences between species is a longstanding question in evolutionary biology. How new genes form and selection acts to produce differenc[...]
2025 | articles |
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Background: Mathematical models are powerful tools to study COVID-19. However, one fundamental challenge in current modeling approaches is the lack of accurate and compre[...]
2021 | articles |
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Background Principal component analysis (PCA) is commonly applied to the atomic trajectories of biopolymers to extract essential dynamics that describe biologically relev[...]
2021 | articles |
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Background: Essential Dynamics (ED) is a common application of principal component analysis (PCA) to extract biologically relevant motions from atomic trajectories of pro[...]
2017 | articles |
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Background: Gram-negative bacteria use periplasmic-binding proteins (bPBP) to transport nutrients through the periplasm. Despite immense diversity within the recognized s[...]
2008 | articles |
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The bacterial enzyme beta-lactamase hydrolyzes the beta-lactam ring of penicillin and chemically related antibiotics, rendering them ineffective. Due to rampant antibioti[...]
2013 | articles |
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Although APE2 plays essential roles in base excision repair and ATR-Chk1 DNA damage response (DDR) pathways, it remains unknown how the APE2 gene is altered in the human [...]
2020 | articles |
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10.
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Previous works have demonstrated that protein rigidity is related to thermodynamic stability, especially under conditions that favor formation of native structure. Mechan[...]
2012 | articles |
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