Search results | J. Murrey Atkins Library

Title: Cytosolic DNA sensors and glial responses to endogenous DNA
Author: Marriott, Ian, Suptela, Alexander J.
Date Created: 2023
Subjects--Topical: Genomics, DNA
Description: Genomic instability is a key driving force for the development and progression of many neurodegenerative diseases and central nervous system (CNS) cancers. The initiation of DNA damage responses is a critical step in maintaining genomic integrity ...

Title: Integrated Genome Browser App Store
Author: Loraine, Ann, Freese, Nowlan H., Shanbhag, Sameer, Shanbhag, Sameer
Date Created: 2022
Subjects--Topical: Genomics, Application software--Development, Information visualization
Description: Rapid progress in genome science requires equally rapid visualization software development so that researchers can better explore and understand novel datasets. To make developing new visualizations faster and easier, we previously re-factored the...

Title: Gene polymorphisms among Plasmodium vivax geographical isolates and the potential as new biomarkers for gametocyte detection
Author: Janies, Daniel, Lo, Eugenia, Ford, Anthony
Date Created: 2022
Subjects--Topical: Genomics, Biology
Description: The unique biological features of Plasmodium vivax not only make it difficult to control but also to eliminate. For the transmission of the malaria parasite from infected human to the vector, gametocytes play a major role. The transmission potenti...

Title: EchinoDB : an update to the web-based application for genomic and transcriptomic data on echinoderms
Author: Janies, Daniel
Date Created: 2022
Subjects--Topical: Genomics, Biology
Description: Background: Here we release a new version of EchinoDB, EchinoDB v2.0 (https://echinodb.uncc.edu). EchinoDB is a database of genomic and transcriptomic data on echinoderms. The initial database consisted of groups of 749,397 orthologous and paralog...

Title: A subterminal growth zone at arm tip likely underlies life-long indeterminate growth in brittle stars
Author: Janies, Daniel, Machado, Denis Jacob, Reid, Robert, Kofsky, Janice
Date Created: 2022
Subjects--Topical: Genomics, Biology
Description: Background Echinoderms are a phylum of marine invertebrates with close phylogenetic relationships to chordates. Many members of the phylum Echinodermata are capable of extensive post-traumatic regeneration and life-long indeterminate growth. Diffe...

Title: Twinkle twinkle brittle star : the draft genome of Ophioderma brevispinum (Echinodermata: Ophiuroidea) as a resource for regeneration research
Author: Janies, Daniel, Machado, Denis Jacob, Reid, Robert, Kofsky, Janice
Date Created: 2022
Subjects--Topical: Genomics, Biology
Description: Background Echinoderms are established models in experimental and developmental biology, however genomic resources are still lacking for many species. Here, we present the draft genome of Ophioderma brevispinum, an emerging model organism in the f...

Title: Active Notch signaling is required for arm regeneration in a brittle star
Author: Janies, Daniel, Machado, Denis Jacob, Reid, Robert
Date Created: 2020
Subjects--Topical: Genomics, Biology
Description: Cell signaling pathways play key roles in coordinating cellular events in development. The Notch signaling pathway is highly conserved across all multicellular animals and is known to coordinate a multitude of diverse cellular events, including pr...

Title: The first complete mitochondrial genome of the sand dollar Sinaechinocyamus mai (Echinoidea: Clypeasteroida)
Author: Janies, Daniel, Machado, Denis Jacob
Date Created: 2020
Subjects--Topical: Genomics, Biology
Description: Morphologic and molecular data often lead to different hypotheses of phylogenetic relationships. Such incongruence has been found in the echinoderm class Echinoidea. In particular, the phylogenetic status of the order Clypeasteroida is not well re...

Title: A new strategy to infer circularity applied to four new complete frog mitogenomes
Author: Machado, Denis Jacob, Janies, Daniel, Brouwer, Cory, Grant, Taran
Date Created: 2018
Subjects--Topical: Genomics, Amphibians, Bioinformatics
Description: We applied a novel strategy to infer sequence circularity and complete assembly of four mitochondrial genomes (mitogenomes) of the frog families Bufonidae (Melanophryniscus moreirae), Dendrobatidae (Hyloxalus subpunctatus and Phyllobates terribili...

Title: Changing of the genomic pattern of Salmonella enteritidis strains isolated in Brazil over a 48 year-period revealed by whole genome SNP analyses
Author: Janies, Daniel
Date Created: 2018
Subjects--Topical: Genomics, Salmonella
Description: Salmonella Enteritidis became the main serovar isolated from gastroenteritis cases in Brazil after the 90's. In this study we used whole genome sequence analysis to determine the phylogenetic relationships among a collection of strains isolated in...

Title: Integration of phylogenomics and molecular modeling reveals lineage-specific diversification of toxins in scorpions
Author: Janies, Daniel, Rush, Nathaniel, Witter, Zachary, Williams, John
Date Created: 2018
Subjects--Topical: Genomics, Biology
Description: Scorpions have evolved a variety of toxins with a plethora of biological targets, but characterizing their evolution has been limited by the lack of a comprehensive phylogenetic hypothesis of scorpion relationships grounded in modern, genome-scale...

Title: Venomix : a simple bioinformatic pipeline for identifying and characterizing toxin gene candidates from transcriptomic data
Author: Janies, Daniel, Reitzel, Adam M., Macrander, Jason
Date Created: 2018
Subjects--Topical: Genomics, Biology
Description: The advent of next-generation sequencing has resulted in transcriptome-based approaches to investigate functionally significant biological components in a variety of non-model organism. This has resulted in the area of venomics: a rapidly growing ...

Title: Salt tolerance response revealed by RNA-Seq in a diploid halophytic wild relative of sweet potato
Author: Loraine, Ann, Luo, Yan, Reid, Robert, Song, Bao-Hua
Date Created: 2017
Subjects--Topical: Genomics, Crop improvement
Description: Crop wild relatives harbor exotic and novel genetic resources, which hold great potential for crop improvement. Ipomoea imperati is a wild diploid relative of sweet potato with the capability of high salinity tolerance. We compared the transcripto...

Title: EchinoDB, an application for comparative transcriptomics of deeply-sampled clades of echinoderms
Author: Janies, Daniel, Witter, Zachary, Linchangco, Gregorio V., Jr.
Date Created: 2016
Subjects--Topical: Genomics, Biology
Description: Background: One of our goals for the echinoderm tree of life project (http://echinotol.org) is to identify orthologs suitable for phylogenetic analysis from next-generation transcriptome data. The current dataset is the largest assembled for echin...

Title: RNA-Seq analysis and annotation of a draft blueberry genome assembly identifies candidate genes involved in fruit ripening, biosynthesis of bioactive compounds, and stage-specific alternative splicing
Author: Loraine, Ann, Gupta, Vikas, Estrada, April, Blakley, Ivory
Date Created: 2015
Subjects--Topical: Genomics, Antioxidants
Description: Background: Blueberries are a rich source of antioxidants and other beneficial compounds that can protect against disease. Identifying genes involved in synthesis of bioactive compounds could enable the breeding of berry varieties with enhanced he...

Title: Phylogeny of echinoderm hemoglobins
Author: Janies, Daniel, Linchangco, Gregorio V., Jr.
Date Created: 2015
Subjects--Topical: Genomics, Biology
Description: Background Recent genomic information has revealed that neuroglobin and cytoglobin are the two principal lineages of vertebrate hemoglobins, with the latter encompassing the familiar myoglobin and alpha-globin/beta-globin tetramer hemoglobin, and ...

Title: Phylotranscriptomic analysis uncovers a wealth of tissue inhibitor of metalloproteinases variants in echinoderms
Author: Janies, Daniel, Clouse, Ronald M., Linchangco, Gregorio V., Jr.
Date Created: 2015
Subjects--Topical: Genomics, Biology
Description: Tissue inhibitors of metalloproteinases (TIMPs) help regulate the extracellular matrix (ECM) in animals, mostly by inhibiting matrix metalloproteinases (MMPs). They are important activators of mutable collagenous tissue (MCT), which have been exte...

Title: Genoviz Software Development Kit : Java tool kit for building genomics visualization applications
Author: Loraine, Ann, Helt, Gregg A., Nicol, John W., Erwin, Ed
Date Created: 2009
Subjects--Topical: Genomics, Software
Description: Background: Visualization software can expose previously undiscovered patterns in genomic data and advance biological science. Results: The Genoviz Software Development Kit (SDK) is an open source, Java-based framework designed for rapid assembly ...

Title: Genome-scale cluster analysis of replicated microarrays using shrinkage correlation coefficient
Author: Loraine, Ann, Yao, Jianchao, Chang, Chunqi, Roux, Stanley J.
Date Created: 2008
Subjects--Topical: Genomics, Bioinformatics
Description: Background: Currently, clustering with some form of correlation coefficient as the gene similarity metric has become a popular method for profiling genomic data. The Pearson correlation coefficient and the standard deviation (SD)-weighted correlat...

Title: Genetic architecture of early vigor traits in wild soybean
Author: Song, Bao-Hua, Kofsky, Janice, Zhang, Hengyou
Subjects--Topical: Genetics, Genomics, Soybean
Description: A worldwide food shortage has been projected as a result of the current increase in global population and climate change. In order to provide sufficient food to feed more people, we must develop crops that can produce higher yields. Plant early vi...