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grdz_etal_acqch_ir_2022
Acquired chemoresistance can lead to increased resistance of pancreatic cancer cells to oncolytic vesicular stomatitis virus
Grdzelishvili, Valery ; Goad, Dakota ; Bressy, Christian ; Holbrook, Molly
Vesicular stomatitis virus (VSV) is a promising oncolytic virus (OV) against different malignancies, including pancreatic ductal adenocarcinoma (PDAC). Our previous studi[...]
2022 | articles |
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grdzval_etal_celcy_ir_2019
Cell cycle arrest in G2/M phase enhances replication of interferon-sensitive cytoplasmic RNA viruses via inhibition of antiviral gene expression
Grdzelishvili, Valery ; Bressy, Christian ; Droby, Gaith N. ; Maldonado, Bryant D.[...]
Vesicular stomatitis virus (VSV) (a rhabdovirus) and its variant VSV-ΔM51 are widely used model systems to study mechanisms of virus-host interactions. Here, we investiga[...]
2019 | articles |
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grdzval_etal_comon_ir_2017
Combining oncolytic virotherapy with p53 tumor suppressor gene therapy
Grdzelishvili, Valery ; Bressy, Christian ; Hastie, Eric Lawrence
Oncolytic virus (OV) therapy utilizes replication-competent viruses to kill cancer cells, leaving non-malignant cells unharmed. With the first U.S. Food and Drug Administ[...]
2017 | articles |
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