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Different therapeutic nucleic acids (TNAs) can be unified in a single structure by their elongation with short oligonucleotides designed to self-assemble into nucleic aci[...]
2022 | articles |
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Nucleic acid nanoparticles (NANPs) require a carrier to allow for their intracellular delivery to immune cells. Cytokine production, specifically type I and III interfero[...]
2023 | articles |
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Besides being a passive carrier of genetic information, DNA can also serve as an architecture template for the synthesis of novel fluorescent nanomaterials that are arran[...]
2019 | articles |
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RNA aptamers selected to bind fluorophores and activate their fluorescence offer a simple and modular way to visualize native RNAs in cells. Split aptamers which are inac[...]
2018 | articles |
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Infusion reactions (IRs) create a translational hurdle for many novel therapeutics, including those utilizing nanotechnology. Nucleic acid nanoparticles (NANPs) are a nov[...]
2019 | articles |
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RNAi-based technologies have shown biomedical potential; however, safe and efficient delivery of RNA remains a barrier for their broader clinical applications. Nucleic ac[...]
2020 | articles |
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Small interfering RNAs (siRNAs) are potential therapeutic substances due to their gene silencing capability as exemplified by the recent approval by the US Food and Drug [...]
2020 | articles |
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In 2015, the J. Murrey Atkins Library recruited faculty, staff, alumni, and students to submit digital images of photomicrographic art, which were printed and placed on e[...]
2017 | articles |
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