Job satisfaction and burnout are directly related to turnover within the substance abuse counseling field and a variable that could predict burnout and job satisfaction such as spiritual well-being was of interest. This study explored how spiritual well-being predicts job satisfaction and feelings of burnout among substance abuse counselors. The research design included bivariate correlational and regression analyses to evaluate the data from substance abuse counselors who were members of a national organization. Results revealed that spiritual well-being was significantly negatively correlated to burnout and significantly positively correlated to job satisfaction. Furthermore, burnout was significantly negatively correlated to job satisfaction. The two hierarchical multiple regression analyses displayed that spiritual well-being was a predictor of burnout and job satisfaction. The multiple regressions indicated that spiritual well-being accounted for 5% of the variance in substance abuse counselor burnout and spiritual well-being accounted for 6% of the variance in substance abuse counselor job satisfaction. Implications for the fields of counseling, counselor education, and clinical supervision are discussed.