This study examined the factor structure of the Independent Living Scales in two subscales of the measure, Managing Money (MM) and Health and Safety (HS), that have been recommended as most valid for predicting competency adjudications (Quickel & Demakis, 2012). The study was conducted with a clinical sample and a sample of college undergraduates. The clinical sample consisted of 131 individuals with various neurological or psychiatric diagnoses, or diagnoses of mental retardation, who were evaluated for competency. The undergraduate sample consisted of 71 college students. Both samples were administered the ILS-MM and ILS-HS subscales as well as other measures of cognitive and neurological functioning (Mini Mental Status Examination and Trail Making Test A & B). As predicted, results of analyses of covariance indicated that participants from the clinical sample had significantly lower performance scores on all cognitive and functional measures than the undergraduate sample. More importantly, a series of four confirmatory factor analyses (CFA) indicated that items on the MM and HS subscales were accounted for by the Problem-Solving (PS) and Performance/Information (PR) factors in the undergraduate sample. In the clinical sample, the CFA indicated that the two-factor structure was an "acceptable-fit" for the data from the MM subscale, however, the two-factor model did not fit the data from the HS subscale.