This study characterizes four toposequences in two first-order watersheds (4.5 and 6.2 ha) of the SE Piedmont where the entire Holocene source-to-sink system is presumably still intact. Despite a long history of soil and geomorphic research in the southeastern Piedmont focused on sediment accumulation in valley bottoms, there are few investigations into of the nature and dynamics of Holocene hillslope soils and hillslope sediments in low-order watersheds that make up most of the region.Soil profiles and sediment sequences were described for 5 soil pits (~1.5 m deep) per hillslope toposequence. The watersheds are underlain with similar lithologies (felsic metavolcanics) but vary in aspect (N & S) and near a major, high-order river. Samples (n=146) from all 21 soil pits were analyzed for particle size, bulk elemental content, carbon content, pedogenic iron content, and radiocarbon age where available. North-facing hillslopes exhibit more mature soils with higher clay content, less sand, lower pedogenic iron ratios, and higher organic content than their south-facing counterparts. Watersheds more distal from major rivers also exhibit mature soils forming in deeper sediment with higher clay content, lower pedogenic iron ratios, less sand, and higher organic content than their river-proximal counterparts. River proximal hillslopes exhibit more and thicker buried soils with higher values of chemical enrichment for Si/Al than their south-facing counterparts. Clay and silt content are also highest in summit and shoulders of interfluves, and sand and gravel content increase towards the valley bottoms as hillslope sediments thicken. Thus, soil development and sediment mobilization on Piedmont hillslopes vary by aspect and position within Piedmont watersheds, even for hillslopes adjacent to streams of similar orders. The implications of these observations prompt a reevaluation of Piedmont soils, suggesting their formation histories are polygenic.