Hospital-acquired pressure injuries (HAPIs) are nursing-sensitive indicators that can lead to extended hospital stays, infection, and even death. Healthcare organizations are not reimbursed for the care HAPIs require, and it is estimated that HAPI costs in the United States could exceed $26.8 billion annually. A quality improvement project utilizing Kamishibai Cards (K-Cards) with interventions to prevent HAPIs was implemented to determine if implementing K-Cards would decrease HAPI frequency counts. The project occurred on two adult nursing units at one hospital with two non-intervention units for comparison. The project unit nurses were provided education, and K-Cards listing HAPI prevention interventions were placed outside each patient room to serve as a visual cue. HAPI frequency counts were collected and compared during the 12 weeks before and after the K-Cards were implemented. One project unit, medical/surgical/progressive, experienced a 66% reduction in HAPI frequency counts [n = 6 (pre), 2 (post)], while their comparison unit experienced a 200% increase [n = 0 (pre), 2 (post)]. The other project unit, a medical/surgical/intensive care unit, experienced a 15% reduction in HAPI frequency counts [n = 13 (pre), 11 (post)], while their comparison unit experienced no change [n = 2 (pre), 2 (post)]. These results indicate that K-Cards are a promising HAPI reduction strategy for further exploration. Further projects with modified HAPI prevention interventions listed on the K-Cards, longer implementation timeframes, and different project and comparison units may be beneficial to more accurately gauge K-Cards' impact on preventing HAPIs.