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Arabidopsis bioinformatics resources : the current state, challenges, and priorities for the future
Title
Arabidopsis bioinformatics resources : the current state, challenges, and priorities for the future
Author
Loraine, Ann, Doherty, Colleen, Friesner, Joanna, Gregory, Brian
Date Created
2019
Subjects--Topical
Bioinformatics, Arabidopsis thaliana
Description
Effective research, education, and outreach efforts by the Arabidopsis thaliana community, as well as other scientific communities that depend on Arabidopsis resources, depend vitally on easily available and publicly-shared resources. These resour...
ELUCIDATING FUNCTIONAL MECHANISMS IN PROTEINS USING THE DISTANCE CONSTRAINT MODEL
Title
ELUCIDATING FUNCTIONAL MECHANISMS IN PROTEINS USING THE DISTANCE CONSTRAINT MODEL
Author
Singer, Christopher
Date Created
2019
Subjects--Topical
Bioinformatics, Biophysics, Physics
Description
Protein thermodynamics has been shown to be insightful and illuminating to the functional mechanisms behind biological function. By characterizing proteins and protein families according to their enthalpy and entropy we can make inferences to the ...
Functional Analysis of Structural Variation in the 2D and 3D Human Genome
Title
Functional Analysis of Structural Variation in the 2D and 3D Human Genome
Author
Nodzak, Conor
Date Created
2019
Subjects--Topical
Bioinformatics, Genetics
Description
The human genome consists of over 3 billion nucleotides that have an average distance of 3.4 Angstroms between each base, which equates to over two meters of DNA contained within the 125 $\mu m^3$ volume diploid cell nuclei. The dense compaction o...
Genomic Dissection of Complex Trait Variation in Wild Soybean, Glycine soja
Title
Genomic Dissection of Complex Trait Variation in Wild Soybean, Glycine soja
Author
Kofsky, Janice
Date Created
2019
Subjects--Topical
Biology, Bioinformatics, Plant diseases
Description
There is a considerable demand for crop improvement, especially considering the growing population, continuing climatic fluctuations, and rapidly evolving plant pests and pathogens. Crop wild relatives hold great potential in providing beneficial ...
Network-based Pathway Enrichment Analysis for Biological Inference of High-throughput Gene Expression Data
Title
Network-based Pathway Enrichment Analysis for Biological Inference of High-throughput Gene Expression Data
Author
Naderi Yeganeh, Pourya
Date Created
2019
Subjects--Topical
Computer science, Bioinformatics
Description
Pathway enrichment analysis models (PEM) are biological inference approaches that leverage annotated bio-molecular functions for interpreting the underlying processes of gene expression profiles from high-throughput genomic data. Common PEMs negle...
Sequencing and annotation of diploid oat genomes and the investigation of Avena-specific nutrients
Title
Sequencing and annotation of diploid oat genomes and the investigation of Avena-specific nutrients
Author
Walstead, Rachel
Date Created
2019
Subjects--Topical
Bioinformatics, Genetics, Botany
Description
Cultivated hexaploid oat (Avena sativa) has held a significant place within the global crop community for centuries; although its cultivation has decreased over the past century, its nutritional benefits have garnered increased interest for human ...
The Microbiota Multiverse: From Gut to Brain and Beyond
Title
The Microbiota Multiverse: From Gut to Brain and Beyond
Author
Brown, Matthew
Date Created
2019
Subjects--Topical
Microbiology, Bioinformatics
Description
This work explores the microbiomes of diverse biological contexts with various stakeholders and collaborators. It consists of six objectives: the first two relate to interaction between the gut microbiome and host health, the second two investigat...