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Break to build : isothermal assembly of nucleic acid nanoparticles (NANPs) via enzymatic degradation
Title
Break to build : isothermal assembly of nucleic acid nanoparticles (NANPs) via enzymatic degradation
Author
Beasock, Damian, Ha, Anh, Halman, Justin, Afonin, Kirill A.
Date Created
2023
Subjects--Topical
Genetics, Peptides
Description
The intrinsic properties of RNA and DNA biopolymers emphasized by engineered nucleic acid nanoparticles (NANPs) offer accelerated development of next-generation therapies. The rational design of NANPs facilitates programmable architectures intende...
REGULATION OF APE1 BY NEIL3 ZINC FINGER-GRF REPEAT ON SINGLE-STRANDED DNA
Title
REGULATION OF APE1 BY NEIL3 ZINC FINGER-GRF REPEAT ON SINGLE-STRANDED DNA
Author
Ha, Anh
Date Created
2020
Subjects--Topical
Molecular biology, Cytology
Description
Base excision repair (BER) is a critical pathway in repairing single base lesions caused by oxidation, deamination, and alkylation. NEIL3 is a DNA glycosylase which functions in initiating BER pathway by recognizing and removing damaged bases. Alt...