Search results
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Title
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Cytosolic DNA sensors and glial responses to endogenous DNA
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Author
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Marriott, Ian, Suptela, Alexander J.
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Date Created
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2023
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Subjects--Topical
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Genomics, DNA
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Description
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Genomic instability is a key driving force for the development and progression of many neurodegenerative diseases and central nervous system (CNS) cancers. The initiation of DNA damage responses is a critical step in maintaining genomic integrity ...
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Title
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Therapeutic immunomodulation by rationally designed nucleic acids and nucleic acid nanoparticles
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Author
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Afonin, Kirill A., Marriott, Ian, Panigaj, Martin
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Date Created
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2023
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Subjects--Topical
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Nucleic acids, Chemistry
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Description
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The immune system has evolved to defend organisms against exogenous threats such as viruses, bacteria, fungi, and parasites by distinguishing between self and non-self. In addition, it guards us against other diseases, such as cancer, by detecting...
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Title
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Therapeutic immunomodulation by rationally designed nucleic acids and nucleic acid nanoparticles (NANPs)
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Author
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Panigaj, Martin, Skelly, Elizabeth, Beasock, Damian, Marriott, Ian
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Date Created
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2023
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Subjects--Topical
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Immunology, Immune response--Regulation
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Description
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The immune system has evolved to defend organisms against exogenous threats such as viruses, bacteria, fungi, and parasites by distinguishing between self and non-self. In addition, it guards us against other diseases, such as cancer, by detecting...