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EXPERIMENTAL EVOLUTION OF ONCOLYTIC VESICULAR STOMATITIS VIRUSES IN CANCER CELLS
Title
EXPERIMENTAL EVOLUTION OF ONCOLYTIC VESICULAR STOMATITIS VIRUSES IN CANCER CELLS
Author
Seegers, Sara
Date Created
2019
Subjects--Topical
Molecular biology, Virology, Biology
Description
Vesicular stomatitis virus (VSV) based oncolytic viruses are promising agents against various cancers. We have shown that pancreatic ductal adenocarcinoma (PDAC) cell lines exhibit great diversity in susceptibility and permissibility to VSV. Here,...
MOLECULAR MECHANISMS OF RESISTANCE OF PANCREATIC DUCTAL ADENOCARCINOMA CELLS TO ONCOLYTIC VESICULAR STOMATITIS VIRUS
Title
MOLECULAR MECHANISMS OF RESISTANCE OF PANCREATIC DUCTAL ADENOCARCINOMA CELLS TO ONCOLYTIC VESICULAR STOMATITIS VIRUS
Author
Felt, Sebastien
Date Created
2017
Subjects--Topical
Molecular biology, Virology, Cytology
Description
Oncolytic virus (OV) therapy is an anticancer therapy using replication-competent viruses selectively infecting, replicating in and killing cancer cells. Human pancreatic ductal adenocarcinoma (PDAC) cell lines are highly heterogeneous in their pe...