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CHARACTERIZING NEXT-GENERATION SEQUENCING (NGS) PLATFORMS FOR MULTIPLEXED BIOSENSING AND APTAMER DISCOVERY: G-QUADRUPLEX APTAMERS AS A CASE STUDY
Title
CHARACTERIZING NEXT-GENERATION SEQUENCING (NGS) PLATFORMS FOR MULTIPLEXED BIOSENSING AND APTAMER DISCOVERY: G-QUADRUPLEX APTAMERS AS A CASE STUDY
Author
Patil, Sushant
Date Created
2016
Subjects--Topical
Molecular biology, Bioinformatics, Biochemistry
Description
Aptamers are single-stranded DNA or RNA molecules forming unique three dimensional structures that can bind to their targets (generally proteins or metabolites or other nucleic acids) with high specificity and affinity. Screening for aptamers requ...
Investigating the Molecular Mechanisms of Essential Oils on Human Health
Title
Investigating the Molecular Mechanisms of Essential Oils on Human Health
Author
Uppal, Aneeta
Date Created
2020
Subjects--Topical
Molecular biology, Bioinformatics, Botany
Description
The essential oil (EO) industry continues to grow as consumers search for more alternative and complementary therapies. When possible, EO users often turn to EOs for basic medical ailments instead of traditional medications/pharmaceuticals. With t...
Investigation and Analysis of Context Dependent Mutation Rates Contribution to Synonymous Mutation Codon Usage via Development of CDMAP.
Title
Investigation and Analysis of Context Dependent Mutation Rates Contribution to Synonymous Mutation Codon Usage via Development of CDMAP.
Author
Patton, David
Date Created
2022
Subjects--Topical
Bioinformatics, Molecular biology, Biometry
Description
Mutations play a pivotal role as a driver of genome evolution in organisms across the tree of life. However, site-specific mutation rates appear to have a non-uniform mutation rate and vary across the genome. Currently, site-specific variation has...
Pleiotropic effects on the transcriptome and genome of transgenic soybeans resulting from transgene integration and expression in seed tissue
Title
Pleiotropic effects on the transcriptome and genome of transgenic soybeans resulting from transgene integration and expression in seed tissue
Author
Lambirth, Kevin
Date Created
2015
Subjects--Topical
Molecular biology, Biology, Bioinformatics
Description
The seeds of the common soybean (Glycine max) produce and store large amounts of protein, making them an appealing bioreactor for producing valuable recombinant proteins at high levels. However, the effects of accumulating recombinant protein at h...