Search results
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Title
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A new strategy to infer circularity applied to four new complete frog mitogenomes
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Author
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Machado, Denis Jacob, Janies, Daniel, Brouwer, Cory, Grant, Taran
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Date Created
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2018
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Subjects--Topical
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Genomics, Amphibians, Bioinformatics
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Description
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We applied a novel strategy to infer sequence circularity and complete assembly of four mitochondrial genomes (mitogenomes) of the frog families Bufonidae (Melanophryniscus moreirae), Dendrobatidae (Hyloxalus subpunctatus and Phyllobates terribili...
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Title
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Active Notch signaling is required for arm regeneration in a brittle star
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Author
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Janies, Daniel, Machado, Denis Jacob, Reid, Robert
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Date Created
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2020
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Subjects--Topical
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Genomics, Biology
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Description
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Cell signaling pathways play key roles in coordinating cellular events in development. The Notch signaling pathway is highly conserved across all multicellular animals and is known to coordinate a multitude of diverse cellular events, including pr...
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Title
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Cytosolic DNA sensors and glial responses to endogenous DNA
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Author
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Marriott, Ian, Suptela, Alexander J.
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Date Created
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2023
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Subjects--Topical
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Genomics, DNA
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Description
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Genomic instability is a key driving force for the development and progression of many neurodegenerative diseases and central nervous system (CNS) cancers. The initiation of DNA damage responses is a critical step in maintaining genomic integrity ...
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Title
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EchinoDB, an application for comparative transcriptomics of deeply-sampled clades of echinoderms
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Author
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Janies, Daniel, Witter, Zachary, Linchangco, Gregorio V., Jr.
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Date Created
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2016
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Subjects--Topical
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Genomics, Biology
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Description
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Background: One of our goals for the echinoderm tree of life project (http://echinotol.org) is to identify orthologs suitable for phylogenetic analysis from next-generation transcriptome data. The current dataset is the largest assembled for echin...
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Title
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Genome-scale cluster analysis of replicated microarrays using shrinkage correlation coefficient
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Author
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Loraine, Ann, Yao, Jianchao, Chang, Chunqi, Roux, Stanley J.
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Date Created
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2008
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Subjects--Topical
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Genomics, Bioinformatics
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Description
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Background: Currently, clustering with some form of correlation coefficient as the gene similarity metric has become a popular method for profiling genomic data. The Pearson correlation coefficient and the standard deviation (SD)-weighted correlat...
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Title
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Integrated Genome Browser App Store
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Author
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Loraine, Ann, Freese, Nowlan H., Shanbhag, Sameer, Shanbhag, Sameer
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Date Created
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2022
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Subjects--Topical
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Genomics, Application software--Development, Information visualization
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Description
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Rapid progress in genome science requires equally rapid visualization software development so that researchers can better explore and understand novel datasets. To make developing new visualizations faster and easier, we previously re-factored the...
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Title
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Integration of phylogenomics and molecular modeling reveals lineage-specific diversification of toxins in scorpions
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Author
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Janies, Daniel, Rush, Nathaniel, Witter, Zachary, Williams, John
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Date Created
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2018
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Subjects--Topical
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Genomics, Biology
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Description
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Scorpions have evolved a variety of toxins with a plethora of biological targets, but characterizing their evolution has been limited by the lack of a comprehensive phylogenetic hypothesis of scorpion relationships grounded in modern, genome-scale...
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Title
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Phylogeny of echinoderm hemoglobins
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Author
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Janies, Daniel, Linchangco, Gregorio V., Jr.
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Date Created
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2015
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Subjects--Topical
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Genomics, Biology
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Description
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Background Recent genomic information has revealed that neuroglobin and cytoglobin are the two principal lineages of vertebrate hemoglobins, with the latter encompassing the familiar myoglobin and alpha-globin/beta-globin tetramer hemoglobin, and ...
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Title
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RNA-Seq analysis and annotation of a draft blueberry genome assembly identifies candidate genes involved in fruit ripening, biosynthesis of bioactive compounds, and stage-specific alternative splicing
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Author
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Loraine, Ann, Gupta, Vikas, Estrada, April, Blakley, Ivory
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Date Created
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2015
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Subjects--Topical
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Genomics, Antioxidants
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Description
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Background: Blueberries are a rich source of antioxidants and other beneficial compounds that can protect against disease. Identifying genes involved in synthesis of bioactive compounds could enable the breeding of berry varieties with enhanced he...
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Title
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Salt tolerance response revealed by RNA-Seq in a diploid halophytic wild relative of sweet potato
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Author
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Loraine, Ann, Luo, Yan, Reid, Robert, Song, Bao-Hua
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Date Created
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2017
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Subjects--Topical
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Genomics, Crop improvement
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Description
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Crop wild relatives harbor exotic and novel genetic resources, which hold great potential for crop improvement. Ipomoea imperati is a wild diploid relative of sweet potato with the capability of high salinity tolerance. We compared the transcripto...