Search results | J. Murrey Atkins Library

Title: Utilizing fluorescently tagged undecaprenyl phosphate as a means to study lipid A modification in Bordetella pertussis.
Author: Black, Theresa
Date Created: 2022
Subjects--Topical: Chemistry
Description: Bordetella pertussis is a gram-negative bacterium that is the causative agent of whooping cough, a highly contagious disease that can be fatal in very young children. The outer membrane of the bacteria consists mainly of lipolysaccharide (LPS), an...

Title: UNDERSTANDING THE EFFECTS OF PERIPHERAL ALKYL SUBSTITUENTS ON EXCITON DIFFUSION PROPERTIES OF PORPHYRIN THIN FILMS FOR ORGANIC PHOTOVOLTAIC APPLICATIONS
Author: Kaushal, Meesha
Date Created: 2019
Subjects--Topical: Materials science, Chemistry
Description: Understanding exciton diffusion is a crucial step in the engineering and fabrication of organic photovoltaic (OPV) devices. We studied a variety of organic dyes in our research lab including various derivatives of carboalkoxyphenylporphyrins in so...

Title: Toll-like receptor-mediated recognition of nucleic acid nanoparticles (NANPs) in human primary blood cells
Author: Afonin, Kirill A., Truong, Nguyen, Halman, Justin
Date Created: 2019
Subjects--Topical: Nucleic acids, Chemistry
Description: Infusion reactions (IRs) create a translational hurdle for many novel therapeutics, including those utilizing nanotechnology. Nucleic acid nanoparticles (NANPs) are a novel class of therapeutics prepared by rational design of relatively short olig...

Title: Therapeutic immunomodulation by rationally designed nucleic acids and nucleic acid nanoparticles
Author: Afonin, Kirill A., Marriott, Ian, Panigaj, Martin
Date Created: 2023
Subjects--Topical: Nucleic acids, Chemistry
Description: The immune system has evolved to defend organisms against exogenous threats such as viruses, bacteria, fungi, and parasites by distinguishing between self and non-self. In addition, it guards us against other diseases, such as cancer, by detecting...

Title: The recognition of and reactions to nucleic acid nanoparticles by human immune cells
Author: Afonin, Kirill A., Bila, Dominika, Panigaj, Martin
Date Created: 2021
Subjects--Topical: Nucleic acids, Chemistry
Description: The relatively straightforward methods of designing and assembling various functional nucleic acids into nanoparticles offer advantages for applications in diverse diagnostic and therapeutic approaches. However, due to the novelty of this approach...

Title: The immunorecognition, subcellular compartmentalization, and physicochemical properties of nucleic acid nanoparticles can be controlled by composition modification
Author: Afonin, Kirill A., Marriott, Ian, Halman, Justin
Date Created: 2020
Subjects--Topical: Nucleic acids, Chemistry
Description: Nucleic acid nanoparticles (NANPs) have become powerful new platforms as therapeutic and diagnostic tools due to the innate biological ability of nucleic acids to identify target molecules or silence genes involved in disease pathways. However, th...

Title: TRINUCLEAR METAL CHALCOGENIDE CLUSTERS AS PRECURSORS FOR SUPERATOMIC SOLIDS AND CLUSTER ORGANIC FRAMEWORKS
Author: Shott, Jessica
Date Created: 2017
Subjects--Topical: Nanoscience, Chemistry, Chemistry, Inorganic
Description: Inorganic molecular clusters Ni3(μ3-I)2(μ2-dppm)3 (1), Ni3(μ3-Te)2(μ2-dppm)3 (2), Ni3(μ3-Se)2(μ2-dppm)3 (3), Ni3(μ3-S)2(μ2-dppm)3 (4), Co4(μ3-S)4(PPri3)4 (5), and Mo3(μ3-S)2(μ2-S)3(PMe3)6 (6) have been used as building block precursors in the form...

Title: THE SYNTHESIS OF PHOTOSENSITIZERS FOR THE PHOTODYNAMIC INACTIVATION OF ESCHERICHIA COLI
Author: Hurst, Alexandra
Date Created: 2017
Subjects--Topical: Chemistry
Description: The development of antibiotic resistance is a natural phenomenon that occurs when bacteria cells exchange resistant traits amongst each other or when mutations occur during replication. This causes bacteria to be able to withstand attack by antibi...

Title: THE SYNTHESIS AND PHOTOPHYSICAL CHARACTERIZATION OF PORPHYRIN PHOTOACTIVE MATERIALS FOR USE AS SENSITIZERS IN ORGANIC PHOTOVOLTAICS AND PHOTODYNAMIC THERAPY
Author: Marin, Dawn
Date Created: 2017
Subjects--Topical: Nanoscience, Chemistry, Physical and theoretical, Chemistry
Description: Solar energy conversion and photodynamic therapy (PDT) are very different applications. However, both utilize very similar photoactive molecules called porphyrins. Porphyrins are structural analogs of chlorophyll and also function as prosthetic gr...

Title: Synthesis, photophysical characterization, and application of asymmetric thiazolothiazoles as molecular sensors
Author: Sayresmith, Nickolas
Date Created: 2021
Subjects--Topical: Nanoscience, Chemistry
Description: Small molecule fluorophores are critical for fluorescence spectroscopy, and enable the measurement of a wide array of biological processes and dynamics. For many biological sensing applications, the overall efficacy of the fluorophore is closely c...

Title: Synthesis, Reactivity, and Applications of Benzimidazole Thiones and Selones
Author: Hernandez, Lizeth
Date Created: 2016
Subjects--Topical: Chemistry
Description: Benzimidazole-2-thiols and their transition metal complexes have been the focus of intense research due to their potential applications in bioinorganic and organometallic chemistry. Within this field of research, the synthesis and reactivity of be...

Title: Synthesis, Characterization, and Reactivity of Cross-Conjugated Frameworks
Author: Hamilton, Victoria
Date Created: 2018
Subjects--Topical: Chemistry, Chemistry, Organic
Description: ABSTRACTVICTORIA LEIGH HAMILTON. Synthesis, Characterization, and Reactivity of Cross-Conjugated Frameworks. (Under the direction of MARKUS ETZKORN)Molecules with cross-conjugated -systems possess unique structures and reactivity due to their dis...

Title: Synthesis, Characterization and Functionalization of Anti-Bisarene Scaffolds
Author: Franklin, Joseph
Date Created: 2017
Subjects--Topical: Chemistry
Description: Since the advent of rational organic synthesis, practitioners in the field have been refining their craft to target compounds of immense complexity. Synthetic methodologies discovered through these pursuits have provided a fertile ground to expand...

Title: Synthesis of Asymmetric Thiazolo[5,4-d] Thiazole Derivatives for Molecular Sensing Applications
Author: Meadows, Jared
Date Created: 2021
Subjects--Topical: Chemistry, Biochemistry, Materials science
Description: This thesis outlines the synthesis and characterization of new asymmetrically substituted thiazolo[5,4-d]thiazole (TTz) compounds. This class of compounds contains a central bicyclic heteroaromatic system that is electron-deficient, and when subst...

Title: Synthesis and characterization of single-walled carbon nanotubes for use in water purification
Author: Johnson, Billy
Date Created: 2016
Subjects--Topical: Materials science, Nanoscience, Chemistry
Description: As human health concerns over disinfection byproducts (DBPs) in drinking water increase, so does the need to development new materials that remove them rapidly and at high-efficiency. Ion exchange (IEX) is an effective method for the removal of na...

Title: Synthesis and Reactivity of Six-Membered N-Heterocyclic Chalcogenones
Author: Flanagan, Jerrod
Date Created: 2017
Subjects--Topical: Chemistry, Chemistry, Inorganic
Description: The synthesis and coordination chemistry of N-heterocyclic thione (NHT) and selone (NHSe) ligands containing a saturated pyrimidine ring and bulky aromatic substituents on the nitrogen atoms is described in this thesis. To further understand the e...

Title: Synthesis and Optical Properties of Hybrid Gold Nanoparticles Coupled with Quantum Dots and Porphyrins
Author: Tobias, Andrew
Date Created: 2016
Subjects--Topical: Nanoscience, Chemistry, Nanotechnology
Description: Coupling of optically active materials, or chromphores, to plasmonic nanoparticles represents a new research area which has the ability to produce higher efficiency lighting and photovoltaic materials. The main goal of this project was to create n...

Title: Synthesis and Electrochemical Characterization of [3]Radialene-based Catholytes for Aqueous Organic Redox Flow Batteries
Author: Turner, Nicholas
Date Created: 2020
Subjects--Topical: Chemistry
Description: The unsubstituted [n]radialenes are a unique class of alicyclic hydrocarbons with radiating alkenes. These compounds are typically difficult to handle and polymerize rapidly. A number of stable radialene derivatives that exhibit reversible electro...

Title: Synthesis and Characterization of Electroactive Organosilanes
Author: Lee, David
Date Created: 2015
Subjects--Topical: Chemistry
Description: Siloles, or silacyclopentadienes, have unique electronic properties due to interaction between the butadiene π* orbital and the silylene σ* orbital. Consequently they have drawn interest for use in a variety of organic electronic interactions. A s...

Title: Special issue nanotechnology to overcome the world's most critical health issues: liposomes and beyond-a themed issue dedicated to Professor Yechezkel Barenholz
Author: Afonin, Kirill A., Dobrovolskaia, Marina
Date Created: 2023
Subjects--Topical: Nucleic acids, Chemistry