Search results
- Title
- A WATER-SOLUBLE COBALT SULFIDE SUPERATOM FOR FLOW BATTERY APPLICATIONS AND CRYSTALLINE FRAMEWORK SYNTHESIS
- Author
- Freeman, Matthew
- Date Created
- 2019
- Subjects--Topical
- Chemistry
- Description
- Metal sulfide clusters are attractive components for flow batteries owing to the abundance of their constituent atoms and their tunable size, solubility, and redox properties. We prepared an atomically precise cobalt sulfide cluster, Co6S8(PTA)6•4...
- Title
- Analysis and Development of Targeting Strategies for Bacterial Sugars
- Author
- Erickson, Katelyn
- Date Created
- 2018
- Subjects--Topical
- Chemistry, Biochemistry
- Description
- Bacterial cell surface exopolysaccharides aid in protecting microbes from the defense mechanisms of the host, and differ substantially in structure between species. Exploiting these structural differences would be advantageous to target certain ty...
- Title
- Artificial immune cell, AI-cell, a new tool to predict interferon production by peripheral blood monocytes in response to nucleic acid nanoparticles
- Author
- Afonin, Kirill A., Chandler, Morgan, Halman, Justin
- Date Created
- 2022
- Subjects--Topical
- Nucleic acids, Chemistry
- Description
- Nucleic acid nanoparticles, or NANPs, rationally designed to communicate with the human immune system, can offer innovative therapeutic strategies to overcome the limitations of traditional nucleic acid therapies. Each set of NANPs is unique in th...
- Title
- Biomotors, viral assembly, and rna nanobiotechnology: current achievements and future directions
- Author
- Afonin, Kirill A., Rolband, Lewis
- Date Created
- 2022
- Subjects--Topical
- Nucleic acids, Chemistry
- Description
- The International Society of RNA Nanotechnology and Nanomedicine (ISRNN) serves to further the development of a wide variety of functional nucleic acids and other related nanotechnology platforms. To aid in the dissemination of the most recent adv...
- Title
- Bis(bipyridyl)silicon(IV) Diols as Potential Dual Hydrogen Bond Donors for Catalysis
- Author
- Waters, Crystal
- Date Created
- 2016
- Subjects--Topical
- Chemistry
- Description
- Hydrogen bond donors (HBDs) have been explored as potential catalysts for the 1,4-conjugate addition and Diels-Alder reactions. HBD catalysis, which relies on Brønsted acid catalytic sites, is being explored as an oxygen and moisture stable altern...
- Title
- Bis(bipyridyl)silicon(IV) compounds – synthesis, characterization, and catalytic properties.
- Author
- Maguylo, Christina
- Date Created
- 2015
- Subjects--Topical
- Chemistry, Chemistry, Inorganic
- Description
- A series of novel hexacoordinate bis-bipyridylsilicon(IV) complexes have been synthesized by reacting [Si(bipy)2I2]I2 with the appropriate alcohol or diol. Characterization was done and crystal structures have been obtained for the complexes: [Si(...
- Title
- Broccoli fluorets : split aptamers as a user-friendly fluorescent toolkit for dynamic RNA nanotechnology
- Author
- Afonin, Kirill A., Chandler, Morgan, Halman, Justin
- Date Created
- 2018
- Subjects--Topical
- Nucleic acids, Chemistry
- Description
- RNA aptamers selected to bind fluorophores and activate their fluorescence offer a simple and modular way to visualize native RNAs in cells. Split aptamers which are inactive until the halves are brought within close proximity can become useful fo...
- Title
- Change in lipofectamine carrier as a tool to fine-tune immunostimulation of nucleic acid nanoparticles
- Author
- Afonin, Kirill A., Newton, Hannah S., Xu, Jie
- Date Created
- 2023
- Subjects--Topical
- Nucleic acids, Chemistry
- Description
- Nucleic acid nanoparticles (NANPs) require a carrier to allow for their intracellular delivery to immune cells. Cytokine production, specifically type I and III interferons, allows for reliable monitoring of the carrier effect on NANP immunostimul...
- Title
- Characterization of cationic bolaamphiphile vesicles for sirna delivery into tumors and brain
- Author
- Afonin, Kirill A., Kim, Taejin, Gupta, Kshitij
- Date Created
- 2020
- Subjects--Topical
- Nucleic acids, Chemistry
- Description
- Small interfering RNAs (siRNAs) are potential therapeutic substances due to their gene silencing capability as exemplified by the recent approval by the US Food and Drug Administration (FDA) of the first siRNA therapeutic agent (patisiran). Howeve...
- Title
- Chemical Tools for Biology
- Author
- Fessler, Adam
- Date Created
- 2017
- Subjects--Topical
- Chemistry
- Description
- Reagents for biotinylation that are innately water-soluble and can be tracked by both UV-vis spectroscopy and fluorescence (330nm/420nm) have been developed. These reagents are based on the isatoic anhydride platform, which gives rise to their val...
- Title
- Complex Glycan Synthesis in Bacteria
- Author
- Wallen, Timothy
- Date Created
- 2019
- Subjects--Topical
- Chemistry
- Description
- Glycans, which are assembled through a process known as glycosylation, are critical for creating biological structures important for the function and vitality of bacterial cells. In order to study the synthesis of glycans, enzymes and intermediate...
- Title
- Conditioning of Platinum Nanoparticle Catalysts for Improved Hydrogen Generation on P3HT:PCBM Bulk Heterojunction Photocathodes
- Author
- Ivins, Reynolds
- Date Created
- 2015
- Subjects--Topical
- Chemistry, Environmental engineering, Renewable energy sources
- Description
- This work aims to design, develop, and investigate the capacity of a metal catalyst-coated organic photoelectrode to produce molecular hydrogen when illuminated in acidic media. 3-5 nm platinum nanoparticles (PtNPs) were synthesized, treated to re...
- Title
- Crystalline Silicon Interfaces with Adhesive Polymer Semiconducting Glue and Thiazolothiazole Redox Active Organic Small Molecules
- Author
- Cohen, Daniel
- Date Created
- 2020
- Subjects--Topical
- Materials science, Chemistry, Chemistry, Organic
- Description
- Crystalline silicon is an extremely versatile semiconductor material used for electronics and photovoltaic devices. An organic conductive glue based on a blend of poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) and d-sorbitol ...
- Title
- DESIGN, SYNTHESIS AND CHARACTERIZATION OF MULTIFUNCTIONAL REDOX-RESPONSIVE PORPHYRIN-BASED POLYSILSESQUIOXANE NANOMATERIALS FOR PHOTODYNAMIC THERAPY
- Author
- Vega, Daniel
- Date Created
- 2015
- Subjects--Topical
- Materials science, Chemistry, Nanotechnology
- Description
- Photodynamic Therapy (PDT) is a minimally invasive clinically approved cancertreatment that was first applied in the early 20th century. PDT is an attractive alternative when compared to chemotherapy and radiation therapy due to the lack of harmfu...
- Title
- DISTANCE-DEPENDENCE OF PLASMON-MULTIEXCITON COUPLING BETWEEN CDSE QUANTUM DOTS AND GOLD NANOSTRUCTURES
- Author
- Castaneda, Jose
- Date Created
- 2015
- Subjects--Topical
- Chemistry, Chemistry, Physical and theoretical
- Description
- Quantum confinement that semiconductors experience at the nanoscale facilitate the creation of multiexcitons. However, this same confinement also increases the efficiency of Auger recombination which result in low quantum yields from these states....
- Title
- DNA-templated fluorescent silver nanoclusters inhibit bacterial growth while being non-toxic to mammalian cells
- Author
- Afonin, Kirill A., Chandler, Morgan, Rolband, Lewis
- Date Created
- 2021
- Subjects--Topical
- Nucleic acids, Chemistry
- Description
- Silver has a long history of antibacterial effectiveness. The combination of atomically precise metal nanoclusters with the field of nucleic acid nanotechnology has given rise to DNA-templated silver nanoclusters (DNA-AgNCs) which can be engineere...
- Title
- Design and Modulation of Novel Chemical Probes for RNA SHAPE Analysis: Water Soluble Isatoic Anhydrides and Nicotinic Acid Imidazolides
- Author
- Fessler, Adam
- Date Created
- 2021
- Subjects--Topical
- Chemistry, Biology
- Description
- The growing interest in RNA biology, along with an expansion in computational capabilities, throughput, and sensitivity has provided researchers new tools to probe RNA. RNA selective 2′-hydroxy acylation analyzed by primer extension (SHAPE) utiliz...
- Title
- Determining the Rate of Ligand-Induced Charge-Transfer Effects on Quantum Dots
- Author
- Bowman, Cale
- Date Created
- 2015
- Subjects--Topical
- Chemistry
- Description
- In this report, charge carrier dynamics and rate of electron transfer is investigated between two bis(thioether)silane (R2BtsMe) ligands and 2.65 nm CdSe core quantum dots (QDs). Isothermal titration calorimetry (ITC) data is used to determine bin...
- Title
- Development of a Surface Enhanced Raman Spectroscopy-based Assay to Detect Malaria Biomarkers in Blood
- Author
- Hamm, Logan
- Date Created
- 2020
- Subjects--Topical
- Chemistry
- Description
- Malaria is an infectious disease that affects many lives around the world and eradication efforts are focused on controlling the disease transmission; which requires early diagnosis of the infection before the onset of symptoms, i.e. at the asympt...
- Title
- Development of nanoparticle-based approaches for the treatment and imaging of pancreatic cancer
- Author
- Tarannum, Mubin
- Date Created
- 2020
- Subjects--Topical
- Nanoscience, Chemistry
- Description
- Pancreatic ductal adenocarcinoma (PDAC) is a type of exocrine pancreatic cancer which accounts for over 90% of cases. PDAC is the fourth-leading cause of cancer-related mortality in the United States with a 5-year survival rate of 9% with little t...