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STRUCTURAL AND FUNCTIONAL ANALYSIS OF THE H19Y MUTATED PRIMARY DNA RECOGNITION SUBDOMAIN OF SLEEPING BEAUTY TRANSPOSASE
Title
STRUCTURAL AND FUNCTIONAL ANALYSIS OF THE H19Y MUTATED PRIMARY DNA RECOGNITION SUBDOMAIN OF SLEEPING BEAUTY TRANSPOSASE
Author
Leighton, Gage
Date Created
2017
Subjects--Topical
Physics, Chemistry, Physical and theoretical, Biophysics
Description
The Sleeping Beauty transposon system, consisting of the transposon DNA and the transposase enzyme, is a member of the Tc1/mariner family of DNA transposons. Although it is an important tool in genetic applications and has been adapted for human g...
SUBSURFACE THERMAL COAGULATION OF TISSUES USING NEAR INFRARED LASERS
Title
SUBSURFACE THERMAL COAGULATION OF TISSUES USING NEAR INFRARED LASERS
Author
Chang, Chun-Hung
Date Created
2017
Subjects--Topical
Optics, Biophysics, Biomedical engineering
Description
Noninvasive laser therapy is currently limited primarily to cosmetic dermatological applications such as skin resurfacing, hair removal, tattoo removal and treatment of vascular birthmarks. In order to expand applications of noninvasive laser ther...
UNDERSTANDING BIAS IN NEXT-GENERATION SEQUENCING TECHNOLOGIES AND ANALYSES
Title
UNDERSTANDING BIAS IN NEXT-GENERATION SEQUENCING TECHNOLOGIES AND ANALYSES
Author
Price, Adam
Date Created
2017
Subjects--Topical
Biology, Bioinformatics, Biophysics
Description
The problem of bias resulting from biological and technological sources is one that must be consistently reexamined alongside the development of new technologies and methods of analysis. This dissertation addresses the complexities of bias identif...