Search results | J. Murrey Atkins Library

Title: A Data-Analytic Approach Towards Increasing Donor Heart Utilization in the United States
Author: Satyanarayana, Sagar
Date Created: 2018
Subjects--Topical: Biometry
Description: Heart transplantation is the best option available to treat end-stage Heart Failure (HF). There is a shortage of donor hearts in the United States even with the steady increase in the number of donors. One likely reason is the decreasing transplan...

Title: Analysis of failure time data with missing and informative auxiliary covariates.
Author: Ghosh, Lipika
Date Created: 2011
Subjects--Topical: Statistics, Mathematics, Biometry
Description: In this dissertation we use Cox's regression model to failure time data with continuous informative auxiliary variables in the presence of a validation subsample. The work is motivated by a common problem of missing or mismeasured covariates in su...

Title: Generalized semiparametric varying-coefficient models for longitudinal data
Author: Qi, Li
Date Created: 2015
Subjects--Topical: Mathematics, Statistics, Biometry
Description: In this dissertation, we investigate the generalized semiparametric varying-coefficient models for longitudinal data that can flexibly model three types of covariate effects: time-constant effects, time-varying effects, and covariate-varying effec...

Title: Improving Semiparametric Estimation of Longitudinal Data with Covariance Function
Author: Fang, Fang
Date Created: 2018
Subjects--Topical: Mathematics, Statistics, Biometry
Description: In this dissertation, we aim to improve efficiency of estimation in longitudinal data under generalized semi-parametric varying-coefficient models.First, we investigate a profile weighted least square approach for model estimation by utilizing wit...

Title: Investigating Multidrug Resistance in Escherichia coli with Phylogenetics and Machine Learning
Author: Brown, David
Date Created: 2023
Subjects--Topical: Bioinformatics, Biometry, Computer science
Description: The next pandemic is already underway in the proliferation of antimicrobial resistance(AMR) genes that reduce the effectiveness of therapeutics. The lessened potency of these current drugs results in increased economic costs, higher public health ...

Title: Investigation and Analysis of Context Dependent Mutation Rates Contribution to Synonymous Mutation Codon Usage via Development of CDMAP.
Author: Patton, David
Date Created: 2022
Subjects--Topical: Bioinformatics, Molecular biology, Biometry
Description: Mutations play a pivotal role as a driver of genome evolution in organisms across the tree of life. However, site-specific mutation rates appear to have a non-uniform mutation rate and vary across the genome. Currently, site-specific variation has...

Title: Semiparametric Additive Hazards Models with Missing Covariates
Author: Subedi, Pramesh
Date Created: 2021
Subjects--Topical: Statistics, Biometry
Description: The case-cohort study design was originally proposed by Prentice (1986). Under this design,a random sub-cohort of individuals is selected from the cohort of study. Full covariate data are collected from all the cases in the cohort and the sub-coho...

Title: Statistical Inference of Semiparametric Cox-Aalen Transformation Models with Failure Time Data
Author: Ning, Xi
Date Created: 2023
Subjects--Topical: Biometry, Statistics
Description: Failure time data are commonly encountered in epidemiological and biomedical studies, where the exact time of an event may be unknown or incomplete. Many semiparametric models have been developed in the literature to analyze such data; however, th...

Title: Statistical estimation and inference for the associations of multivariate recurrent event processes
Author: Chen, Peilin
Date Created: 2019
Subjects--Topical: Statistics, Biometry
Description: In this dissertation, we aim to develop a brand new method with a two-stage procedure to investigate the association between multivariate recurrent event processes. First, under the assumption of independent censoring, we model each recurrent even...

Title: Towards Ending the HIV Epidemic One County at a Time an Evaluation Framework for Subcounty-level Usage of Pre-exposure Prophylaxis for Exposing Disparities and Guiding Targeted Interventions
Author: Satyanarayana, Sagar
Date Created: 2021
Subjects--Topical: Biometry, Epidemiology, Statistics
Description: About 1.1 million Americans were living with HIV in 2019 with the total lifetime cost to treat a single person with an HIV infection estimated to be around $501,000. Huge disparities in new HIV incidences exist between different geographic and dem...

Title: UNDERSTANDING GENOME-WIDE GENE REGULATION IN PROKARYOTES USING OMICS DATA
Author: Seyedi Tabari, Seyed Ehsan
Date Created: 2016
Subjects--Topical: Bioinformatics, Information science, Biometry
Description: Gene annotation is a critical step for understanding functions of genomes and host organisms. However, accurately annotating thousands of sequenced genomes can be a challenging task. Further, although gene transcriptional regulation is crucial for...