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FACTORS SHED BY BREAST TUMOR CELLS, TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME ACTIVITIES, AND THE GENERATION OF PRO-TUMOR MACROPHAGES
Title
FACTORS SHED BY BREAST TUMOR CELLS, TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME ACTIVITIES, AND THE GENERATION OF PRO-TUMOR MACROPHAGES
Author
Rego, Stephen
Date Created
2013
Subjects--Topical
Biology
Description
The role of the tumor microenvironment, especially of tumor associated macrophages (TAMs), in the progression and metastatic spread of breast cancer is well established. TAMs are activated in the breast tumor microenvironment to express primarily ...
Fungal Treatments for Lignocellulosic Bioconversion
Title
Fungal Treatments for Lignocellulosic Bioconversion
Author
Giles, Richard
Date Created
2013
Subjects--Topical
Power resources, Biology
Description
Four studies were conducted to develop an innovative application of fungal biopulping technologies to improve commercialization of lignocellulosic ethanol biofuel production using sustainable waste products. The first study focused on evaluation a...
INTERACTIVE EFFECTS OF OCEAN ACIDIFICATION AND MULTIPLE STRESSORS ON PHYSIOLOGY OF MARINE BIVALVES
Title
INTERACTIVE EFFECTS OF OCEAN ACIDIFICATION AND MULTIPLE STRESSORS ON PHYSIOLOGY OF MARINE BIVALVES
Author
Matoo, Omera
Date Created
2013
Subjects--Topical
Biology, Ecology
Description
The continuing increase of carbon dioxide (CO2) levels in the atmosphere leads to increase in sea-surface temperature and causes ocean acidification altering seawater carbonate chemistry. Estuarine and shallow coastal areas, which are hotspots for...
Long-term study of changes in microbiota in a Cystic Fibrosis patient
Title
Long-term study of changes in microbiota in a Cystic Fibrosis patient
Author
Stokell, Joshua
Date Created
2013
Subjects--Topical
Biology, Microbiology
Description
Application of culture-independent techniques have revealed the presence of more types of bacteria than were previously thought, which led to the current description of Cystic Fibrosis (CF) being a polymicrobial disease. We know this polymicrobial...
NOVEL ROLES OF MICRORNAS IN HEPATITIS C
Title
NOVEL ROLES OF MICRORNAS IN HEPATITIS C
Author
Sendi, Hossein
Date Created
2013
Subjects--Topical
Virology, Biology
Description
Approximately, 170 million people are infected by hepatitis C virus (HCV) worldwide, and of these, nearly 85% will develop chronic hepatitis C (CHC). Despite finding new anti-viral treatment that increase response rate from 45 % to 65-70 %, invest...
THE DEVELOPMENT OF NOVEL THERAPEUTICS IN PANCREATIC AND BREAST CANCERS: POTENTIAL ROLE OF MUC1
Title
THE DEVELOPMENT OF NOVEL THERAPEUTICS IN PANCREATIC AND BREAST CANCERS: POTENTIAL ROLE OF MUC1
Author
Besmer, Dahlia
Date Created
2013
Subjects--Topical
Biology
Description
Pancreatic ductal adenocarcinoma (PDA) is the 4th leading cause of cancer-related deaths in the US, and breast cancer (BC) contributes to ~40,000 deaths annually. The development of novel therapeutic agents for improving patient outcome is of para...
Variations within class-a beta-lactamase physiochemical properties reflect evolutionary and environmental patterns, but not antibiotic specificity
Title
Variations within class-a beta-lactamase physiochemical properties reflect evolutionary and environmental patterns, but not antibiotic specificity
Author
Jacobs, Donald J., Verma, Deeptak, Livesay, Dennis R.
Date Created
2013
Subjects--Topical
Biology, Bacteria
Description
The bacterial enzyme beta-lactamase hydrolyzes the beta-lactam ring of penicillin and chemically related antibiotics, rendering them ineffective. Due to rampant antibiotic overuse, the enzyme is evolving new resistance activities at an alarming ra...