Search results
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Title
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ALGORITHMS FOR STRUCTURE BASED-PREDICTION OF TRANSCRIPTION FACTOR BINDING SITES
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Author
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Farrel, Alvin
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Date Created
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2016
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Subjects--Topical
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Computer science, Biology, Bioinformatics
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Description
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Transcription factors (TFs) regulate gene expression through binding to specific target DNA sites. Accurate annotation of transcription factor binding sites (TFBSs) at genome scale represents an essential step toward our understanding of gene regu...
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Title
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COMPARATIVE ANALYSIS OF REPEAT LANDSCAPES IN AVENA (OAT)
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Author
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Burkes, Shelvasha
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Date Created
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2020
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Subjects--Topical
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Biology, Bioinformatics, Botany
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Description
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Avena sativa, or common oat, is a staple crop and member of the Poaceae or Grass family. Following behind wheat, maize and rice, oats account for 10.5 million hectares of the world’s produced crops as of 2017. Phytocompounds such as β-glucan, aven...
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Title
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Toward understanding protein-DNA interactions
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Author
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Lin, Maoxuan
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Date Created
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2020
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Subjects--Topical
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Biology, Bioinformatics, Biochemistry
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Description
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Knowledge of protein-DNA interactions has important implications in understandingbiological activities and developing therapeutic drugs. Two types of protein-DNAinteractions exist: (1) interactions between double-stranded DNA-binding proteins(DSBs...
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Title
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UNDERSTANDING BIAS IN NEXT-GENERATION SEQUENCING TECHNOLOGIES AND ANALYSES
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Author
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Price, Adam
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Date Created
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2017
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Subjects--Topical
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Biology, Bioinformatics, Biophysics
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Description
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The problem of bias resulting from biological and technological sources is one that must be consistently reexamined alongside the development of new technologies and methods of analysis. This dissertation addresses the complexities of bias identif...