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FACTORS SHED BY BREAST TUMOR CELLS, TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME ACTIVITIES, AND THE GENERATION OF PRO-TUMOR MACROPHAGES
Title
FACTORS SHED BY BREAST TUMOR CELLS, TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME ACTIVITIES, AND THE GENERATION OF PRO-TUMOR MACROPHAGES
Author
Rego, Stephen
Date Created
2013
Subjects--Topical
Biology
Description
The role of the tumor microenvironment, especially of tumor associated macrophages (TAMs), in the progression and metastatic spread of breast cancer is well established. TAMs are activated in the breast tumor microenvironment to express primarily ...
Inflammation, NLRP3 Inflammasomes, Macrophages and Breast Cancer Progression
Title
Inflammation, NLRP3 Inflammasomes, Macrophages and Breast Cancer Progression
Author
Holtzman , Katherine
Date Created
2021
Subjects--Topical
Biology, Immunology, Oncology
Description
One in 8 women will be diagnosed with breast cancer in their lifetime and while breast cancer mortality has declined since the 1980s, it remains the 2nd leading cause of cancer-related deaths among women. Standard of care is determined by anatomic...
Periostin and TGFBI in Breast Cancer Progression
Title
Periostin and TGFBI in Breast Cancer Progression
Author
Phelps, Michelle
Date Created
2015
Subjects--Topical
Biology, Cytology
Description
Dynamic interactions between cancer cells, supportive stromal cells, the extracellular matrix (ECM), and the immune system are critical to breast cancer progression. Periostin is an ECM protein correlated to poor outcomes in breast cancer. Periost...