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NUCLEIC ACID-DRIVEN QUANTUM DOT-BASED LATTICE FORMATIONS FOR BIOMEDICAL APPLICATIONS
Title
NUCLEIC ACID-DRIVEN QUANTUM DOT-BASED LATTICE FORMATIONS FOR BIOMEDICAL APPLICATIONS
Author
Roark, Brandon
Date Created
2017
Subjects--Topical
Nanoscience, Nanotechnology, Biochemistry
Description
We present a versatile biosensing strategy that uses nucleic acids programmed to undergo an isothermal toehold mediated strand displacement in the presence of analyte. This rearrangement results in a double biotinylated duplex formation that induc...
RNA Kissing Loop Library to expand RNA Fiber functionality and control cargo load for potential intracellular siRNA delivery.
Title
RNA Kissing Loop Library to expand RNA Fiber functionality and control cargo load for potential intracellular siRNA delivery.
Author
Shevchenko, Oleg
Date Created
2020
Subjects--Topical
Nanoscience, Nanotechnology, Biochemistry
Description
A kissing loop (KL) is an RNA motif that among others may have a 180° geometry when derived from a viral genome. The KL interactions of this geometry consist of nine base pairs, six of which are interacting in complementary binding while three are...