Search results
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Title
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Analysis and Development of Targeting Strategies for Bacterial Sugars
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Author
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Erickson, Katelyn
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Date Created
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2018
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Subjects--Topical
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Chemistry, Biochemistry
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Description
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Bacterial cell surface exopolysaccharides aid in protecting microbes from the defense mechanisms of the host, and differ substantially in structure between species. Exploiting these structural differences would be advantageous to target certain ty...
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Title
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CO-CHAPERONE REGULATION OF THE RIBONUCLOETIDE REDUCTASE COMPLEX
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Author
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Knighton, Laura
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Date Created
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2020
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Subjects--Topical
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Biology, Biochemistry
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Description
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The molecular chaperone Hsp70 folds a significant proportion of the proteome and is responsible for the activity and stability of many disease-related proteins, including those in cancer. Substantial effort has been devoted to developing a range o...
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Title
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FUNCTIONAL NUCLEIC ACID NANOPARTICLES AND THEIR DELIVERY
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Author
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Ke, Weina
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Date Created
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2020
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Subjects--Topical
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Biochemistry, Cytology
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Description
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Nucleic acid biopolymers are essential to all living organisms. The chemical makeup of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) consist of sequences of only four monomers. However, they transmit and express genetic information for va...
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Title
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Regulation of Myosin IIIa Motor/Kinase Activity
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Author
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Moore, Judy
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Date Created
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2009
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Subjects--Topical
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Biochemistry, Neurosciences, Cytology
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Description
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Myosin IIIa, a motor protein that localizes to actin-rich regions of photoreceptors and to stereocilia of inner ear hair cells, is associated with the hearing process in vertebrates and with phototransduction for invertebrates. It contains a large...
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Title
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Toward understanding protein-DNA interactions
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Author
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Lin, Maoxuan
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Date Created
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2020
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Subjects--Topical
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Biology, Bioinformatics, Biochemistry
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Description
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Knowledge of protein-DNA interactions has important implications in understandingbiological activities and developing therapeutic drugs. Two types of protein-DNAinteractions exist: (1) interactions between double-stranded DNA-binding proteins(DSBs...
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Title
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Understanding Chaperone interactions in disease
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Author
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Nitika
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Date Created
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2021
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Subjects--Topical
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Molecular biology, Biochemistry, Cytology
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Description
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The correct folding of proteins after synthesis and stress-promoted denaturation is critical for cell viability in all organisms. The Hsp70 molecular chaperone is a key player in proteostasis, deciding which proteins are foldable and which are too...
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Title
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VPS501, A NOVEL SNX-BAR PROTEIN INVOLVED IN AUTOPHAGY
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Author
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goyal, Shreya
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Date Created
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2021
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Subjects--Topical
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Biochemistry, Cytology, Molecular biology
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Description
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ABSTRACTCareful control of intracellular signaling pathways plays an important role in a cell’s ability to maintain stable internal conditions in the face of an ever-changing extracellular environment. This is particularly true as it relates to th...