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Assessments of Indel Annotation Programs and Comparative Somatic Indel Analysis in Cancer Genomes
Title
Assessments of Indel Annotation Programs and Comparative Somatic Indel Analysis in Cancer Genomes
Author
Chen, Jing
Date Created
2020
Subjects--Topical
Bioinformatics
Description
Insertions and deletions (indels) represent the second largest variation type in human genomes and have been implicated in the development of cancer. Accurate indel annotation is of paramount importance in variants analysis in both healthy and dis...
COMPARATIVE ANALYSIS OF REPEAT LANDSCAPES IN AVENA (OAT)
Title
COMPARATIVE ANALYSIS OF REPEAT LANDSCAPES IN AVENA (OAT)
Author
Burkes, Shelvasha
Date Created
2020
Subjects--Topical
Biology, Bioinformatics, Botany
Description
Avena sativa, or common oat, is a staple crop and member of the Poaceae or Grass family. Following behind wheat, maize and rice, oats account for 10.5 million hectares of the world’s produced crops as of 2017. Phytocompounds such as β-glucan, aven...
DO DYNAMIC ALLOSTERIC EFFECTS OCCUR IN IGG4 ANTIBODIES?
Title
DO DYNAMIC ALLOSTERIC EFFECTS OCCUR IN IGG4 ANTIBODIES?
Author
Baker, Lonnie
Date Created
2020
Subjects--Topical
Bioinformatics, Biophysics
Description
Antibodies are large, multi-chain proteins which play a critical roll in the func-tioning of vertebrate immune systems. Immune effector cells which are responsiblefor the destruction of foreign antigens do not randomly target molecules but rely on...
Genetic and metabolomic characterization of wild soybean in response to soybean cyst nematode (Heterodera glycine)
Title
Genetic and metabolomic characterization of wild soybean in response to soybean cyst nematode (Heterodera glycine)
Author
Mittal, Neha
Date Created
2020
Subjects--Topical
Bioinformatics, Agriculture
Description
Crops harvesting ensure human survival on earth. However, sustainable crop production is challenging because of continuous biotic stresses caused by different pests (e.g., nematodes, bacteria, fungi, viruses, and insects). Soybean (Glycine max) is...
Investigating the Molecular Mechanisms of Essential Oils on Human Health
Title
Investigating the Molecular Mechanisms of Essential Oils on Human Health
Author
Uppal, Aneeta
Date Created
2020
Subjects--Topical
Molecular biology, Bioinformatics, Botany
Description
The essential oil (EO) industry continues to grow as consumers search for more alternative and complementary therapies. When possible, EO users often turn to EOs for basic medical ailments instead of traditional medications/pharmaceuticals. With t...
Prediction of Cis-regulatory Modules in Genomes
Title
Prediction of Cis-regulatory Modules in Genomes
Author
Ni, Pengyu
Date Created
2020
Subjects--Topical
Bioinformatics
Description
Annotating all cis-regulatory modules (CRMs) and constituent transcription factor (TF) binding sites (TFBSs) in genomes is essential to understand genome functions, however, the task remains highly challenging. In this dissertation, we first devel...
The influence of wastewater treatment on community dynamics among antibiotic-resistant bacteria during treatment, stream release, and biosolids land application.
Title
The influence of wastewater treatment on community dynamics among antibiotic-resistant bacteria during treatment, stream release, and biosolids land application.
Author
Sorgen, Alicia
Date Created
2020
Subjects--Topical
Microbiology, Bioinformatics, Ecology
Description
Wastewater treatment plants (WWTP) are a key link between anthropogenic activity and the environment, facilitating the development and horizontal transfer of antibiotic resistance among populations of commensal environmental microorganisms and cli...
Toward understanding protein-DNA interactions
Title
Toward understanding protein-DNA interactions
Author
Lin, Maoxuan
Date Created
2020
Subjects--Topical
Biology, Bioinformatics, Biochemistry
Description
Knowledge of protein-DNA interactions has important implications in understandingbiological activities and developing therapeutic drugs. Two types of protein-DNAinteractions exist: (1) interactions between double-stranded DNA-binding proteins(DSBs...