Search results
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Title
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Collateral changes in susceptibility of Burkholderia multivorans
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Author
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Flanagan, Jerilyn
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Date Created
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2019
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Subjects--Topical
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Biology, Microbiology
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Description
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Antibiotic resistant bacteria, particularly in chronic infections, are difficult and costly to treat, so research into detection, identification, and treatment options is critical. Susceptibility measurement must accurately reflect the degree to w...
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Title
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Detrimental brain inflammation and the role of the interleukin 10 family members
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Author
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Burmeister, Amanda
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Date Created
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2019
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Subjects--Topical
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Biology
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Description
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Resident brain cells recognize pathogens and can initiate and/or regulate inflammation. Indeed, we have shown that stimulated glial cells rapidly produce inflammatory mediators, followed by the late production of anti-inflammatory cytokines such a...
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Title
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EXPERIMENTAL EVOLUTION OF ONCOLYTIC VESICULAR STOMATITIS VIRUSES IN CANCER CELLS
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Author
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Seegers, Sara
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Date Created
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2019
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Subjects--Topical
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Molecular biology, Virology, Biology
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Description
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Vesicular stomatitis virus (VSV) based oncolytic viruses are promising agents against various cancers. We have shown that pancreatic ductal adenocarcinoma (PDAC) cell lines exhibit great diversity in susceptibility and permissibility to VSV. Here,...
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Title
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Genomic Dissection of Complex Trait Variation in Wild Soybean, Glycine soja
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Author
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Kofsky, Janice
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Date Created
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2019
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Subjects--Topical
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Biology, Bioinformatics, Plant diseases
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Description
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There is a considerable demand for crop improvement, especially considering the growing population, continuing climatic fluctuations, and rapidly evolving plant pests and pathogens. Crop wild relatives hold great potential in providing beneficial ...
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Title
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MUC1 MEDIATED SIGNALING IN PANCREATIC DUCTAL ADENOCARCINOMA
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Author
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Grover, Priyanka
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Date Created
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2019
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Subjects--Topical
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Biology
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Description
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In 2019, Pancreatic Cancer (PC) is the 3rd leading cause of cancer-related deaths in the USA with 94% dying within 5 years of diagnosis. 90% of PC is Pancreatic Ductal Adenocarcinoma (PDA), of which >80% overexpress a hypo-glycosylated form the me...
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Title
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THE ROLE OF XRCC1 AND POLYMERASE BETA IN GENOME INTEGRITY IN XENOPUS EGG EXTRACTS
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Author
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Cupello, Steven
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Date Created
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2019
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Subjects--Topical
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Molecular biology, Biology, Cytology
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Description
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Cells of organisms are constantly exposed to genomic insults such as oxidative stress from endogenous sources or environmental agents. Oxidative stress induces oxidative DNA damage such as apurinic/apyrimidinic (AP) sites, single-strand breaks (SS...