Search results
-
-
Title
-
ELUCIDATING FUNCTIONAL MECHANISMS IN PROTEINS USING THE DISTANCE CONSTRAINT MODEL
-
Author
-
Singer, Christopher
-
Date Created
-
2019
-
Subjects--Topical
-
Bioinformatics, Biophysics, Physics
-
Description
-
Protein thermodynamics has been shown to be insightful and illuminating to the functional mechanisms behind biological function. By characterizing proteins and protein families according to their enthalpy and entropy we can make inferences to the ...
-
-
Title
-
Functional Analysis of Structural Variation in the 2D and 3D Human Genome
-
Author
-
Nodzak, Conor
-
Date Created
-
2019
-
Subjects--Topical
-
Bioinformatics, Genetics
-
Description
-
The human genome consists of over 3 billion nucleotides that have an average distance of 3.4 Angstroms between each base, which equates to over two meters of DNA contained within the 125 $\mu m^3$ volume diploid cell nuclei. The dense compaction o...
-
-
Title
-
Genomic Dissection of Complex Trait Variation in Wild Soybean, Glycine soja
-
Author
-
Kofsky, Janice
-
Date Created
-
2019
-
Subjects--Topical
-
Biology, Bioinformatics, Plant diseases
-
Description
-
There is a considerable demand for crop improvement, especially considering the growing population, continuing climatic fluctuations, and rapidly evolving plant pests and pathogens. Crop wild relatives hold great potential in providing beneficial ...
-
-
Title
-
The Microbiota Multiverse: From Gut to Brain and Beyond
-
Author
-
Brown, Matthew
-
Date Created
-
2019
-
Subjects--Topical
-
Microbiology, Bioinformatics
-
Description
-
This work explores the microbiomes of diverse biological contexts with various stakeholders and collaborators. It consists of six objectives: the first two relate to interaction between the gut microbiome and host health, the second two investigat...