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Evolution and dynamics of transcriptional regulation in bacteria
Title
Evolution and dynamics of transcriptional regulation in bacteria
Author
Li, Shan
Date Created
2013
Subjects--Topical
Computer science, Statistics, Bioinformatics
Description
Although transcription is one of the most important biological functions of cells, our understanding of its regulation is still limited. In this dissertation, we have studied the transcriptional regulation in prokaryotes in three aspects. First, w...
MICROBIAL CONTRIBUTIONS TO DISEASE PHENOTYPES
Title
MICROBIAL CONTRIBUTIONS TO DISEASE PHENOTYPES
Author
McCafferty, Jonathan
Date Created
2013
Subjects--Topical
Bioinformatics
Description
The unseen world of microbes has a profound affect on everyday life. Complex microbial communities play a role in everything from climate regulation to human health and disease pathogenesis. Advancements in the field of Metagenomics are providing ...
MODELING, SIMULATION AND ANALYSIS OF THE REACTION FIELD FOR ELECTROSTATIC INTERACTIONS IN AQUEOUS SOLUTION
Title
MODELING, SIMULATION AND ANALYSIS OF THE REACTION FIELD FOR ELECTROSTATIC INTERACTIONS IN AQUEOUS SOLUTION
Author
SONG, WEI
Date Created
2013
Subjects--Topical
Computer science, Bioinformatics, Biophysics
Description
How to deal with the long-range electrostatic interactions theoretically and computationally has been well studied due to their importance in biological processes and time consuming summations in computer simulations. The main focus of our researc...
STUDIES ON CORRELATED MUTATIONS ALGORITHMS OF PROTEINS PROVIDING STRUCTURAL, SPATIAL, AND ALLOSTERY INFORMATION FROM MULTIPLE SEQUENCE ALIGNMENTS
Title
STUDIES ON CORRELATED MUTATIONS ALGORITHMS OF PROTEINS PROVIDING STRUCTURAL, SPATIAL, AND ALLOSTERY INFORMATION FROM MULTIPLE SEQUENCE ALIGNMENTS
Author
Kreth, Kyle
Date Created
2013
Subjects--Topical
Bioinformatics
Description
Proteins provide innumerable cellular functions and benefits for all kingdoms in the domains of life. Advancements in the high throughput collection and analysis of proteins have led to ever-deeper understanding of biological pathways, evolution, ...
The effect of structure in short regions of DNA on measurements on short-oligonucleotide microarray and Ion Torrent PGM sequencing platforms
Title
The effect of structure in short regions of DNA on measurements on short-oligonucleotide microarray and Ion Torrent PGM sequencing platforms
Author
Khoshnevis, Saeed
Date Created
2013
Subjects--Topical
Bioinformatics
Description
Single-stranded DNA in solution has been studied by biophysicists for many years, as complex structures, both stable and dynamic, form under normal experimental conditions. Stable intra-strand formations affect enzymatic technical processes such a...
VIBRIO VULNIFICUS VIRULENCE AND SURVIVAL MECHANISMS REVEALED THROUGH COMPARATIVE MICROBIAL GENOMIC ANALYSIS
Title
VIBRIO VULNIFICUS VIRULENCE AND SURVIVAL MECHANISMS REVEALED THROUGH COMPARATIVE MICROBIAL GENOMIC ANALYSIS
Author
Morrison, Shatavia
Date Created
2013
Subjects--Topical
Bioinformatics
Description
A sound genome assembly and robust annotations are essential to the differential analysis of bacterial genomes. Using a case study data set of newly sequenced Vibrio vulnificus genomes, both the biology of these bacteria, and the bioinformatics pr...