Search results
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Title
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Collateral changes in susceptibility of Burkholderia multivorans
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Author
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Flanagan, Jerilyn
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Date Created
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2019
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Subjects--Topical
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Biology, Microbiology
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Description
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Antibiotic resistant bacteria, particularly in chronic infections, are difficult and costly to treat, so research into detection, identification, and treatment options is critical. Susceptibility measurement must accurately reflect the degree to w...
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Title
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Detrimental brain inflammation and the role of the interleukin 10 family members
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Author
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Burmeister, Amanda
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Date Created
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2019
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Subjects--Topical
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Biology
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Description
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Resident brain cells recognize pathogens and can initiate and/or regulate inflammation. Indeed, we have shown that stimulated glial cells rapidly produce inflammatory mediators, followed by the late production of anti-inflammatory cytokines such a...
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Title
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Diel patterning in the bacterial community associated with the sea anemone Nematostella vectensis
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Author
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Reitzel, Adam M., Leach, Whitney B., Carrier, Tyler J.
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Date Created
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2019
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Subjects--Topical
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Gene expression, Biology
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Description
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Microbes can play an important role in the physiology of animals by providing essential nutrients, inducing immune pathways, and influencing the specific species that compose the microbiome through competitive or facilitatory interactions. The com...
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Title
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EXPERIMENTAL EVOLUTION OF ONCOLYTIC VESICULAR STOMATITIS VIRUSES IN CANCER CELLS
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Author
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Seegers, Sara
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Date Created
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2019
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Subjects--Topical
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Molecular biology, Virology, Biology
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Description
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Vesicular stomatitis virus (VSV) based oncolytic viruses are promising agents against various cancers. We have shown that pancreatic ductal adenocarcinoma (PDAC) cell lines exhibit great diversity in susceptibility and permissibility to VSV. Here,...
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Title
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Genomic Dissection of Complex Trait Variation in Wild Soybean, Glycine soja
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Author
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Kofsky, Janice
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Date Created
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2019
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Subjects--Topical
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Biology, Bioinformatics, Plant diseases
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Description
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There is a considerable demand for crop improvement, especially considering the growing population, continuing climatic fluctuations, and rapidly evolving plant pests and pathogens. Crop wild relatives hold great potential in providing beneficial ...
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Title
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Linear mitochondrial genome in Anthozoa (Cnidaria) : a case study in Ceriantharia
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Author
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Reitzel, Adam M., Stampar, Sergio N., Macrander, Jason
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Date Created
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2019
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Subjects--Topical
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Gene expression, Biology
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Description
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Sequences and structural attributes of mitochondrial genomes have played a critical role in the clarification of relationships among Cnidaria, a key phylum of early-diverging animals. Among the major lineages of Cnidaria, Ceriantharia (tube anemon...
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Title
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MUC1 MEDIATED SIGNALING IN PANCREATIC DUCTAL ADENOCARCINOMA
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Author
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Grover, Priyanka
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Date Created
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2019
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Subjects--Topical
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Biology
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Description
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In 2019, Pancreatic Cancer (PC) is the 3rd leading cause of cancer-related deaths in the USA with 94% dying within 5 years of diagnosis. 90% of PC is Pancreatic Ductal Adenocarcinoma (PDA), of which >80% overexpress a hypo-glycosylated form the me...
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Title
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THE ROLE OF XRCC1 AND POLYMERASE BETA IN GENOME INTEGRITY IN XENOPUS EGG EXTRACTS
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Author
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Cupello, Steven
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Date Created
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2019
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Subjects--Topical
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Molecular biology, Biology, Cytology
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Description
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Cells of organisms are constantly exposed to genomic insults such as oxidative stress from endogenous sources or environmental agents. Oxidative stress induces oxidative DNA damage such as apurinic/apyrimidinic (AP) sites, single-strand breaks (SS...
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Title
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Updated phylogeny of chikungunya virus suggests lineage-specific RNA architecture
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Author
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Janies, Daniel
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Date Created
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2019
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Subjects--Topical
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Communicable diseases, Biology
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Description
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Chikungunya virus (CHIKV), a mosquito-borne alphavirus of the family Togaviridae, has recently emerged in the Americas from lineages from two continents: Asia and Africa. Historically, CHIKV circulated as at least four lineages worldwide with both...