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Current perspectives of telomerase structure and function in eukaryotes with emerging views on telomerase in human parasites
Title
Current perspectives of telomerase structure and function in eukaryotes with emerging views on telomerase in human parasites
Author
Chakrabarti, Kausik, Dey, Abhishek
Date Created
2018
Subjects--Topical
Molecular biology, Evolution (Biology)
Description
Replicative capacity of a cell is strongly correlated with telomere length regulation. Aberrant lengthening or reduction in the length of telomeres can lead to health anomalies, such as cancer or premature aging. Telomerase is a master regulator f...
Notch Serves as a Molecular Brake on Myogenesis, Protein Synthesis, and Growth in Skeletal Muscle
Title
Notch Serves as a Molecular Brake on Myogenesis, Protein Synthesis, and Growth in Skeletal Muscle
Author
Huot, Joshua
Date Created
2018
Subjects--Topical
Molecular biology, Kinesiology
Description
Aging can be accompanied by aggressive loss of muscle mass (sarcopenia) and is a primary prognosticator for the reduced capacity of the elderly to accomplish basic activities of daily living. Several mechanisms within skeletal muscle lead to devel...
Dissecting functional differences in Hsp70 isoforms in nematostella vectensis
Title
Dissecting functional differences in Hsp70 isoforms in nematostella vectensis
Author
Waller, Shawn
Date Created
2018
Subjects--Topical
Molecular biology
Description
Heat shock protein 70s (Hsp70s) are a highly conserved class of molecular chaperones that are involved in cellular processes in all organisms such as stress response, homeostatic maintenance, and cell cycle progression. The organism Nematostella v...
ACCURATE AND EFFICIENT CALCULATION OF SINGULAR ELECTROSTATIC POTENTIALS IN CHARGE-DIELECTRIC SPHERICAL AND JANUS PARTICLE SYSTEMS
Title
ACCURATE AND EFFICIENT CALCULATION OF SINGULAR ELECTROSTATIC POTENTIALS IN CHARGE-DIELECTRIC SPHERICAL AND JANUS PARTICLE SYSTEMS
Author
Retz, Caylah
Date Created
2018
Subjects--Topical
Molecular biology, Mathematics, Physics
Description
We introduce an efficient and accurate boundary element method for computing the electrostatic potential in closely-packed dielectric spheres and Janus particles. Close physical proximity occurs in modeling molecular ion interactions or colloidal ...
Inflammasome-driven IL-1ß and IL-18 cytokine signaling between macrophages and cancer cells within the breast tumor microenvironment
Title
Inflammasome-driven IL-1ß and IL-18 cytokine signaling between macrophages and cancer cells within the breast tumor microenvironment
Author
Suryaprakash, Deepika
Date Created
2018
Subjects--Topical
Molecular biology, Oncology
Description
Breast cancer especially triple-negative breast cancer remains deadly, despite detection, monitoring and therapeutic advances. Indeed, aggressive breast cancers metastasize to tissues including the brain, bones, and lungs. Metastasis is favored by...