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ELUCIDATING THE MOLECULAR BASIS OF INHIBITION OF ENZYMES ESSENTIAL FOR BATERIALVIRULENCE: THE ACTIVITY OF THREE GLYCOSYLTRANSFERASES AND A POTENTIAL DRUG TARGET, UNDECAPRENYL PYROPHOSPHATE SYNTHASE
Title
ELUCIDATING THE MOLECULAR BASIS OF INHIBITION OF ENZYMES ESSENTIAL FOR BATERIALVIRULENCE: THE ACTIVITY OF THREE GLYCOSYLTRANSFERASES AND A POTENTIAL DRUG TARGET, UNDECAPRENYL PYROPHOSPHATE SYNTHASE
Author
Okwei, Elleansar
Date Created
2016
Subjects--Topical
Chemistry, Biology, Biochemistry
Description
The fight against bacterial infection is one of the most important branches of modern medicine. Due to the emergence of strains of antibiotic-resistant bacteria, researchers have been presented with complex challenges in an effort to combat these ...
Folate Receptor-Specific, Redox-Responsive Mesoporous Silica Nanoparticles for the Simultaneous Delivery of Cisplatin and Gemcitabine to Treat Cancer
Title
Folate Receptor-Specific, Redox-Responsive Mesoporous Silica Nanoparticles for the Simultaneous Delivery of Cisplatin and Gemcitabine to Treat Cancer
Author
Fink, Eric
Date Created
2016
Subjects--Topical
Materials science, Chemistry, Biochemistry
Description
Nanoparticles are an innovative platform for cancer treatment that reduces systemic toxicity and allows for active targeting of tumor sites to enhance the therapeutic efficacy. Mesoporous silica nanoparticles (MSNs) have emerged as an attractive d...
Exceptional New Reagents for Bioconjugation
Title
Exceptional New Reagents for Bioconjugation
Author
Garmon, Corey
Date Created
2016
Subjects--Topical
Chemistry, Biochemistry
Description
At about the turn of this century the term "click" chemistry came into the common vernacular amongst chemists. "Click" is used to describe reactions that are "spring-loaded" and proceed well in a predictable manner, with no offensive byproduct and...
CHARACTERIZING NEXT-GENERATION SEQUENCING (NGS) PLATFORMS FOR MULTIPLEXED BIOSENSING AND APTAMER DISCOVERY: G-QUADRUPLEX APTAMERS AS A CASE STUDY
Title
CHARACTERIZING NEXT-GENERATION SEQUENCING (NGS) PLATFORMS FOR MULTIPLEXED BIOSENSING AND APTAMER DISCOVERY: G-QUADRUPLEX APTAMERS AS A CASE STUDY
Author
Patil, Sushant
Date Created
2016
Subjects--Topical
Molecular biology, Bioinformatics, Biochemistry
Description
Aptamers are single-stranded DNA or RNA molecules forming unique three dimensional structures that can bind to their targets (generally proteins or metabolites or other nucleic acids) with high specificity and affinity. Screening for aptamers requ...