Search results
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Title
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Dynamic and Conditionally Activated Nucleic Acid Nanoparticles
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Author
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Chandler, Morgan
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Date Created
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2021
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Subjects--Topical
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Nanoscience
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Description
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Programmed interactions of nucleic acids—including DNA and RNA—orchestrate genetic expression and downstream cellular processes at every level. The structures of nucleic acids rely on their sequences, which include traditional Watson-Crick base pa...
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Title
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Exploring the Immune System using Hybrid Cube Nanoparticles
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Author
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McMillan, Jessica
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Date Created
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2021
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Subjects--Topical
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Biochemistry, Nanotechnology, Biology
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Description
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Nano-sized cubes made from nucleic acid material (NANPs) are ideal scaffolds for therapeutic nucleic acids (TNAs). Both utilize sequence specificity through base-pairing, providing controlled strand interaction, stability, and targeted targeting d...
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Title
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FUNCTIONAL NUCLEIC ACID NANOPARTICLES AND THEIR DELIVERY
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Author
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Ke, Weina
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Date Created
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2020
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Subjects--Topical
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Biochemistry, Cytology
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Description
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Nucleic acid biopolymers are essential to all living organisms. The chemical makeup of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) consist of sequences of only four monomers. However, they transmit and express genetic information for va...
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Title
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Immunostimulatory Properties of Nucleic Acid Nanoparticles
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Author
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Halman, Justin
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Date Created
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2020
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Subjects--Topical
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Nanoscience
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Description
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Nucleic acids (DNA and RNA) are ubiquitous biomolecules found throughout all living organisms. They can act as genetic information storage and messengers, enzymes, molecular switches, and much more. Although DNA is used almost exclusively for its ...
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Title
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NUCLEIC ACID-DRIVEN QUANTUM DOT-BASED LATTICE FORMATIONS FOR BIOMEDICAL APPLICATIONS
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Author
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Roark, Brandon
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Date Created
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2017
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Subjects--Topical
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Nanoscience, Nanotechnology, Biochemistry
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Description
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We present a versatile biosensing strategy that uses nucleic acids programmed to undergo an isothermal toehold mediated strand displacement in the presence of analyte. This rearrangement results in a double biotinylated duplex formation that induc...
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Title
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ORGANIZATION OF BIOMOLECULES IN A 3-DIMENSIONAL SPACE
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Author
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Sajja, Sameer
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Date Created
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2019
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Subjects--Topical
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Nanotechnology, Biochemistry
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Description
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The human body operates using various stimuli-responsive mechanisms, dictating biological activity via reaction to external cues. Hydrogels are networked hydrophilic polymeric materials that offer the potential to recreate aqueous environments wit...
