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Evolution and dynamics of transcriptional regulation in bacteria
Title
Evolution and dynamics of transcriptional regulation in bacteria
Author
Li, Shan
Date Created
2013
Subjects--Topical
Computer science, Statistics, Bioinformatics
Description
Although transcription is one of the most important biological functions of cells, our understanding of its regulation is still limited. In this dissertation, we have studied the transcriptional regulation in prokaryotes in three aspects. First, w...
The effect of structure in short regions of DNA on measurements on short-oligonucleotide microarray and Ion Torrent PGM sequencing platforms
Title
The effect of structure in short regions of DNA on measurements on short-oligonucleotide microarray and Ion Torrent PGM sequencing platforms
Author
Khoshnevis, Saeed
Date Created
2013
Subjects--Topical
Bioinformatics
Description
Single-stranded DNA in solution has been studied by biophysicists for many years, as complex structures, both stable and dynamic, form under normal experimental conditions. Stable intra-strand formations affect enzymatic technical processes such a...