Search results | J. Murrey Atkins Library

Title: Analysis and Development of Targeting Strategies for Bacterial Sugars
Author: Erickson, Katelyn
Date Created: 2018
Subjects--Topical: Chemistry, Biochemistry
Description: Bacterial cell surface exopolysaccharides aid in protecting microbes from the defense mechanisms of the host, and differ substantially in structure between species. Exploiting these structural differences would be advantageous to target certain ty...

Title: Assessing the Impact of Buffer Salt Choice on the Formation of DNA I-Motifs
Author: West, Caroline
Date Created: 2023
Subjects--Topical: Chemistry
Description: I-motifs are intercalated cytosine quadruplexes discovered in 1993, but they weren’t shown to exist in the cell nucleus until 2018. While their biological role has yet to be fully elucidated, they have been implicated in regulating expression of s...

Title: BIOFLAVONOIDS GENISTEIN AND QUERCETIN TRIGGER ALTERNATIVE END JOINING PATHWAY OF DNA REPAIR
Author: GHOSH, ANINDITA
Date Created: 2019
Subjects--Topical: Biology
Description: Faithful repair of chromosomal double-strand breaks (DSBs) is crucial to genome stability and normal cell survival and proliferation. During normal metabolic processes and especially following exposure to DNA damaging agents including irradiation,...

Title: Characterization of Dynamic and Functional Nucleic Acid Based Systems
Author: Beasock, Damian
Date Created: 2023
Subjects--Topical: Nanoscience
Description: Nucleic acids are highly integrated into molecular biology and exhibit very interesting character. They have immense engineering potential to improve human health and influence molecular systems. Consequently, these biopolymers are the quintessent...

Title: Characterization of the Colanic Acid Biosynthesis Pathway with a Fluorescent Bactoprenyl Monophosphate Analogue
Author: Scott, Phillip
Date Created: 2015
Subjects--Topical: Biochemistry
Description: When introduced to harsh conditions such as low pH, pathogenic Escherichia coli can secrete colanic acid, an exopolysaccharide that completely engulfs the organism, to establish a protective barrier between the organism and the acidic environment....

Title: Complex Glycan Synthesis in Bacteria
Author: Wallen, Timothy
Date Created: 2019
Subjects--Topical: Chemistry
Description: Glycans, which are assembled through a process known as glycosylation, are critical for creating biological structures important for the function and vitality of bacterial cells. In order to study the synthesis of glycans, enzymes and intermediate...

Title: DISTANCE-DEPENDENCE OF PLASMON-MULTIEXCITON COUPLING BETWEEN CDSE QUANTUM DOTS AND GOLD NANOSTRUCTURES
Author: Castaneda, Jose
Date Created: 2015
Subjects--Topical: Chemistry, Chemistry, Physical and theoretical
Description: Quantum confinement that semiconductors experience at the nanoscale facilitate the creation of multiexcitons. However, this same confinement also increases the efficiency of Auger recombination which result in low quantum yields from these states....

Title: Dynamic and Conditionally Activated Nucleic Acid Nanoparticles
Author: Chandler, Morgan
Date Created: 2021
Subjects--Topical: Nanoscience
Description: Programmed interactions of nucleic acids—including DNA and RNA—orchestrate genetic expression and downstream cellular processes at every level. The structures of nucleic acids rely on their sequences, which include traditional Watson-Crick base pa...

Title: ELUCIDATING THE MOLECULAR BASIS OF INHIBITION OF ENZYMES ESSENTIAL FOR BATERIALVIRULENCE: THE ACTIVITY OF THREE GLYCOSYLTRANSFERASES AND A POTENTIAL DRUG TARGET, UNDECAPRENYL PYROPHOSPHATE SYNTHASE
Author: Okwei, Elleansar
Date Created: 2016
Subjects--Topical: Chemistry, Biology, Biochemistry
Description: The fight against bacterial infection is one of the most important branches of modern medicine. Due to the emergence of strains of antibiotic-resistant bacteria, researchers have been presented with complex challenges in an effort to combat these ...

Title: INCORPORATION OF FLUORESCENT ANALOGUES IN ISOPRENOID PATHWAYS IN ESCHERICHIA COLI
Author: George, Chelsea
Date Created: 2018
Subjects--Topical: Biochemistry
Description: Bacterial glycans and glycoconjugates have wide diversity compared to their eukaryotic counterparts. While methods have been developed to monitor and track glycans in eukaryotic systems with some success, there are limited methods with which to do...

Title: Immunostimulatory Properties of Nucleic Acid Nanoparticles
Author: Halman, Justin
Date Created: 2020
Subjects--Topical: Nanoscience
Description: Nucleic acids (DNA and RNA) are ubiquitous biomolecules found throughout all living organisms. They can act as genetic information storage and messengers, enzymes, molecular switches, and much more. Although DNA is used almost exclusively for its ...

Title: MUC1 MEDIATED SIGNALING IN PANCREATIC DUCTAL ADENOCARCINOMA
Author: Grover, Priyanka
Date Created: 2019
Subjects--Topical: Biology
Description: In 2019, Pancreatic Cancer (PC) is the 3rd leading cause of cancer-related deaths in the USA with 94% dying within 5 years of diagnosis. 90% of PC is Pancreatic Ductal Adenocarcinoma (PDA), of which >80% overexpress a hypo-glycosylated form the me...

Title: SYNTHESIS OF THIAZOLOTHIAZOLE FUNCTIONALIZED PORPHYRINS FOR ORGANIC SOLAR CELL APPLICATIONS
Author: Grubich, Nicholas
Date Created: 2014
Subjects--Topical: Materials science, Chemistry, Chemistry, Organic
Description: Porphyrin light-harvesting systems have recently shown promising solar energy conversion properties in organic photovoltaic devices. Porphyrins, which absorb a broad portion of the solar spectrum and can be easily tuned with peripheral substituent...

Title: Single-shot Quantitative Phase Microscopy in a Common-path Configuration
Author: Norton, Brandon
Date Created: 2023
Subjects--Topical: Optics, Physics
Description: Quantitative Phase Microscopy (QPM) is a technique frequently used in microscopy togather information about transparent objects that provide a phase shift relative to their background. We propose a technique that employs a liquid crystal in a comm...

Title: Systematic Analysis of Antibiotic Resistance Genes (ARGs) in Water and Environmental System
Author: Park, Sol
Date Created: 2021
Subjects--Topical: Environmental engineering, Bioinformatics, Water resources development--Management
Description: The global research community is aware of the prevalence and ubiquity of antibiotic resistant genes (ARGs) which is increasing over time due to human activities (Allen et al. 2010; Baquero, Martínez, and Cantón 2008; Bergeron et al. 2016; Di Cesar...

Title: THE SYNTHESIS AND PHOTOPHYSICAL CHARACTERIZATION OF PORPHYRIN PHOTOACTIVE MATERIALS FOR USE AS SENSITIZERS IN ORGANIC PHOTOVOLTAICS AND PHOTODYNAMIC THERAPY
Author: Marin, Dawn
Date Created: 2017
Subjects--Topical: Nanoscience, Chemistry, Physical and theoretical, Chemistry
Description: Solar energy conversion and photodynamic therapy (PDT) are very different applications. However, both utilize very similar photoactive molecules called porphyrins. Porphyrins are structural analogs of chlorophyll and also function as prosthetic gr...

Title: The Role of Film Morphology and Defects on the Photostability and Carrier Transport of Methylammonium Lead Triiodide
Author: Castaneda, Jose
Date Created: 2022
Subjects--Topical: Nanoscience, Materials science, Chemistry, Physical and theoretical
Description: Organic-inorganic hybrid perovskites are viewed as a cost-effective alternative for photovoltaic devices, among other applications. Solution and low-temperature processing have gathered much attention for this class of materials. However, the stab...

Title: UV-Based Advanced Oxidation Processes and Nanoscale Antimicrobials for Antibiotic Resistance Mitigation
Author: Sorinolu, Adeola
Date Created: 2022
Subjects--Topical: Environmental engineering, Nanoscience, Microbiology
Description: Antibiotic resistance (AR) is an ongoing pandemic that is unnoticed by many. AR is a global public health issue that challenges therapeutic potential against pathogens of humans and animals. Predictably, the environment has been implicated in the ...

Title: Utilizing fluorescently tagged undecaprenyl phosphate as a means to study lipid A modification in Bordetella pertussis.
Author: Black, Theresa
Date Created: 2022
Subjects--Topical: Chemistry
Description: Bordetella pertussis is a gram-negative bacterium that is the causative agent of whooping cough, a highly contagious disease that can be fatal in very young children. The outer membrane of the bacteria consists mainly of lipolysaccharide (LPS), an...