Search results | J. Murrey Atkins Library

Title: A STRUCTURAL AND FUNCTIONAL ANALYSIS OF NEMATOSTELLA VECTENSIS MAJOR INTRINSIC PROTEINS
Author: Taylor, Jonathon
Date Created: 2020
Subjects--Topical: Biology, Cytology, Evolutionary developmental biology
Description: There is currently a major gap in understanding the physiological processes of tissue grade animals from early diverging phyla, particularly within the context of the molecular mechanisms in response to osmotic variation. A key protein family esse...

Title: ASSESSING COMPARATIVE FUNCTIONS FOR THE BZIP TRANSCRIPTION FACTOR NFE2 IN NEMATOSTELLA VECTENSIS
Author: Clegg, Devin
Date Created: 2020
Subjects--Topical: Biology
Description: The bZIP gene superfamily is a family of transcription factors that have gone through multiple duplication events within bilaterians, specifically in vertebrates. This has led to multiple paralogs in each bZIP family while early diverging phyla ha...

Title: Assessment of Methods and Environmental Influence on the Nematostella Vectensis Microbiome
Author: Krueger, Quinton
Date Created: 2022
Subjects--Topical: Microbiology, Bioinformatics
Description: Cnidarians are a diverse clade of marine invertebrates that inhabit a variety of environments. The conditions of these habitats are becoming more extreme with the progression of time. These organisms associate with bacteria, which are composed of ...

Title: BIOFLAVONOIDS GENISTEIN AND QUERCETIN TRIGGER ALTERNATIVE END JOINING PATHWAY OF DNA REPAIR
Author: GHOSH, ANINDITA
Date Created: 2019
Subjects--Topical: Biology
Description: Faithful repair of chromosomal double-strand breaks (DSBs) is crucial to genome stability and normal cell survival and proliferation. During normal metabolic processes and especially following exposure to DNA damaging agents including irradiation,...

Title: Circadian behavior and gene expression in an estuarine cnidarian, Nematostella vectensis
Author: Leach, Whitney
Date Created: 2019
Subjects--Topical: Molecular biology, Ecology
Description: Animals respond to diurnal shifts in their environment with a combination of behavioral, physiological, and molecular changes to synchronize with regularly-timed external cues. The light:dark cycle is regarded as the most important entrainment cue...

Title: Diagnostic Ultrasound Assessment of Femoral Cartilage Health in Individuals with Patellofemoral Pain
Author: Jeon, Hyunjae
Date Created: 2021
Subjects--Topical: Kinesiology
Description: Patients with patellofemoral pain (PFP) experience pain during or after physical activities. Recent evidence suggests PFP is not only a painful symptom which hinders daily activity but also a potential marker for future development of patellofemor...

Title: EVALUATING BIOFLAVONOID INDUCED DNA DOUBLE-STRAND BREAKS AND CHROMOSOMAL TRANSLOCATIONS
Author: Goodenow, Donna
Date Created: 2020
Subjects--Topical: Biology
Description: Dietary bioflavonoids are a class of chemical compounds found in soy, fruits, vegetables, tea, coffee, wine, and dietary supplements. They are separated into 12 different sub-classes based upon their structure, however only six are dietarily relev...

Title: EXPERIMENTAL EVOLUTION OF ONCOLYTIC VESICULAR STOMATITIS VIRUSES IN CANCER CELLS
Author: Seegers, Sara
Date Created: 2019
Subjects--Topical: Molecular biology, Virology, Biology
Description: Vesicular stomatitis virus (VSV) based oncolytic viruses are promising agents against various cancers. We have shown that pancreatic ductal adenocarcinoma (PDAC) cell lines exhibit great diversity in susceptibility and permissibility to VSV. Here,...

Title: Fibroblast-driven Fibrosis and Inflammation in Breast Cancer Progression
Author: Samuels, Courtney
Date Created: 2022
Subjects--Topical: Biology
Description: Breast cancer progression is promoted by both local inflammation and fibrosis. Indeed,accumulation of fibrous collagen is an independent prognosis marker of breast cancer. However, the mechanisms underlying the interplay between fibroblasts, infla...

Title: Inflammasome-driven IL-1ß and IL-18 cytokine signaling between macrophages and cancer cells within the breast tumor microenvironment
Author: Suryaprakash, Deepika
Date Created: 2018
Subjects--Topical: Molecular biology, Oncology
Description: Breast cancer especially triple-negative breast cancer remains deadly, despite detection, monitoring and therapeutic advances. Indeed, aggressive breast cancers metastasize to tissues including the brain, bones, and lungs. Metastasis is favored by...

Title: MUC1 MEDIATED SIGNALING IN PANCREATIC DUCTAL ADENOCARCINOMA
Author: Grover, Priyanka
Date Created: 2019
Subjects--Topical: Biology
Description: In 2019, Pancreatic Cancer (PC) is the 3rd leading cause of cancer-related deaths in the USA with 94% dying within 5 years of diagnosis. 90% of PC is Pancreatic Ductal Adenocarcinoma (PDA), of which >80% overexpress a hypo-glycosylated form the me...

Title: ROLE OF THE NOVEL DNA SENSORS cGAS, IFI16, AND ZBP1, DURING VIRAL INFECTIONS IN GLIA
Author: Jeffries, Austin
Date Created: 2020
Subjects--Topical: Immunology, Virology, Neurosciences
Description: Viral central nervous system (CNS) infections can lead to life threatening encephalitis and long-term neurological deficits in survivors. Resident CNS cell types, such as astrocytes and microglia, are known to produce key inflammatory and antivira...

Title: Role of Intramolecular Electrostatic Interactions on the Kinetics of Human Cardiac Myosin β-Isoform
Author: Gargey, Akhil
Date Created: 2021
Subjects--Topical: Molecular biology, Biochemistry, Biophysics
Description: Human cardiac myosin has two isoforms, α and β, sharing significant sequence similarity, but different in kinetics. Small differences in the sequence are responsible for distinct local inter-residue interactions within α and β isoforms, leading to...

Title: Role of the DNA Sensors cGAS and ZBP1 in DNA Damage and Viral Infection
Author: Suptela, Alexander
Date Created: 2023
Subjects--Topical: Immunology, Molecular biology, Neurosciences
Description: Genomic instability is a key driving force for the development and progression of many neurodegenerative diseases and central nervous system (CNS) cancers. The initiation of DNA damage responses (DDRs) is a critical step in maintaining genomic int...

Title: Screening of FDA-Approved Drug Library for Combinatorial Treatment of Pancreatic Ductal Adenocarcinoma Cells with Oncolytic Vesicular Stomatitis Virus
Author: Holbrook, Molly
Date Created: 2021
Subjects--Topical: Biology
Description: Pancreatic ductal adenocarcinoma (PDAC) is a devastating malignancy with poor prognosis and a dismal survival rate, expected to become the second leading cause of cancer-related deaths in the United States. Oncolytic virus (OV) is an anticancer ap...

Title: Study of Enzymes Required for the Synthesis of the Enterobacterial Common Antigen in Vitro
Author: Oliverio, Cassidy
Date Created: 2021
Subjects--Topical: Biology
Description: In recent years, the Center for Disease Control (CDC) has highlighted many bacteria as being either serious or urgent threats in terms of antibiotic resistance such as Salmonella enterica, Klebsiella, and Shigella. These bacteria are all members o...

Title: THE ROLE OF XRCC1 AND POLYMERASE BETA IN GENOME INTEGRITY IN XENOPUS EGG EXTRACTS
Author: Cupello, Steven
Date Created: 2019
Subjects--Topical: Molecular biology, Biology, Cytology
Description: Cells of organisms are constantly exposed to genomic insults such as oxidative stress from endogenous sources or environmental agents. Oxidative stress induces oxidative DNA damage such as apurinic/apyrimidinic (AP) sites, single-strand breaks (SS...

Title: The Effectiveness of Video Discharge Instructions for the Newly Diagnosed Pediatric Oncology Caregiver
Author: Mergenthaler, Dawn
Date Created: 2023
Subjects--Topical: Nursing
Description: DAWN MERGENTHALER. THE EFFECTIVENESS OF VIDEO DISCHARGE INSTRUCTIONS FOR THE NEWLY DIAGNOSED PEDIATRIC ONCOLOGY CAREGIVER(Under the direction of DR. KATHLEEN JORDAN)Effective discharge teaching for caregivers of newly diagnosed pediatric oncology ...

Title: The induction of type-I interferon responses in primary osteoblasts following staphylococcus aureus infection
Author: Furr, Kelli
Date Created: 2022
Subjects--Topical: Biology
Description: Osteomyelitis is a serious bacterial infection of bone that is associated with progressive inflammatory tissue damage. This condition commonly affects the long bones of children along with the vertebrae and pelvis of adults. Staphylococcus aureus,...

Title: VPS501, A NOVEL SNX-BAR PROTEIN INVOLVED IN AUTOPHAGY
Author: goyal, Shreya
Date Created: 2021
Subjects--Topical: Biochemistry, Cytology, Molecular biology
Description: ABSTRACTCareful control of intracellular signaling pathways plays an important role in a cell’s ability to maintain stable internal conditions in the face of an ever-changing extracellular environment. This is particularly true as it relates to th...