DNA and RNA are structurally and functionally diverse biopolymers that haveshown promise in recent years as a powerful biomedical tool, in the form of nucleic acid nanotechnologies. The applications of these technologies include biosensing, diagno...
Aptamers are single-stranded DNA or RNA molecules forming unique three dimensional structures that can bind to their targets (generally proteins or metabolites or other nucleic acids) with high specificity and affinity. Screening for aptamers requ...
Nucleic acids are highly integrated into molecular biology and exhibit very interesting character. They have immense engineering potential to improve human health and influence molecular systems. Consequently, these biopolymers are the quintessent...
The growing interest in RNA biology, along with an expansion in computational capabilities, throughput, and sensitivity has provided researchers new tools to probe RNA. RNA selective 2′-hydroxy acylation analyzed by primer extension (SHAPE) utiliz...
Chronic diseases like cancer are characterized by complex interactions between multiple pathways leading to treatment resistance and invasiveness. Repeated cycles of cytotoxic monotherapies are susceptible to drug resistance induced by the upregul...
Cancer is not one disease but many. In fact, cancer is a collection of more than 100 different diseases. Cancer is the second leading cause of death in the United States with an estimated 1.7 million new cases expected in 2017 and approximately 60...
