Search results
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Title
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Characterization of Dynamic and Functional Nucleic Acid Based Systems
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Author
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Beasock, Damian
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Date Created
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2023
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Subjects--Topical
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Nanoscience
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Description
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Nucleic acids are highly integrated into molecular biology and exhibit very interesting character. They have immense engineering potential to improve human health and influence molecular systems. Consequently, these biopolymers are the quintessent...
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Title
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Development of Silica Based Nanoparticles for Multimodal Therapeutic Delivery
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Author
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Vadarevu, Hemapriyadarshini
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Date Created
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2022
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Subjects--Topical
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Nanoscience
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Description
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Chronic diseases like cancer are characterized by complex interactions between multiple pathways leading to treatment resistance and invasiveness. Repeated cycles of cytotoxic monotherapies are susceptible to drug resistance induced by the upregul...
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Title
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ELUCIDATING FUNCTIONAL MECHANISMS IN PROTEINS USING THE DISTANCE CONSTRAINT MODEL
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Author
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Singer, Christopher
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Date Created
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2019
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Subjects--Topical
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Bioinformatics, Biophysics, Physics
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Description
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Protein thermodynamics has been shown to be insightful and illuminating to the functional mechanisms behind biological function. By characterizing proteins and protein families according to their enthalpy and entropy we can make inferences to the ...
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Title
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LOADED AND ELABORATED POLYESTER NANOMATERIALS FOR THE TREATMENT AND DIAGNOSIS OF DISEASE
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Author
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Fowler, Anthony
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Date Created
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2017
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Subjects--Topical
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Chemistry, Nanotechnology
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Description
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Cancer is not one disease but many. In fact, cancer is a collection of more than 100 different diseases. Cancer is the second leading cause of death in the United States with an estimated 1.7 million new cases expected in 2017 and approximately 60...
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Title
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MACROPHAGES EXPRESSING NEUROPILIN-1 AND BREAST TUMOR PROGRESSION
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Author
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Helms, Rachel
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Date Created
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2015
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Subjects--Topical
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Biology
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Description
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Human breast carcinoma is the most commonly diagnosed cancer in women in the United States with patient mortality primarily resulting from metastasis of breast cancer cells to distant organs. Immune cells, including macrophages, are involved in ca...
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Title
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REGULATION OF ACTOMYOSIN ATPASE
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Author
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Ge, Jinghua
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Date Created
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2016
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Subjects--Topical
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Optics, Physics, Biophysics
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Description
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Myosin is a molecular motor that converts chemical energy to mechanical energy, thus generating force and movement in muscles and cells. Myosin interacts with two ligands, ATP (fuel) and actin filaments (motor’s tracks). Actomyosin interaction is ...
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Title
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THE ROLE OF OXYGEN ON THE IN VITRO AND IN SITU ECOPHYSIOLOGY OF MARINE VIBRIO SPECIES
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Author
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Phippen, Britney
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Date Created
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2018
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Subjects--Topical
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Microbiology
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Description
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Hypoxia is an emerging concern in coastal ecosystems worldwide, and the number of areas experiencing hypoxia has increased exponentially in recent years. It is most prevalent in summer months when elevated temperatures lead to increased oxygen con...