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An Evaluation of Teaching Methods in the Introductory Physics Classroom
Title
An Evaluation of Teaching Methods in the Introductory Physics Classroom
Author
Savage, Lauren
Date Created
2015
Subjects--Topical
Education, Physics, Educational evaluation
Description
The introductory physics mechanics course at the University of North Carolina at Charlotte has a history of relatively high DFW rates. In 2011, the course was redesigned from the traditional lecture format to the inverted classroom format (flipped...
Analysis of a Low Enriched Uranium Centrifugal Gas Core Reactor
Title
Analysis of a Low Enriched Uranium Centrifugal Gas Core Reactor
Author
Leer, Darrin
Date Created
2020
Subjects--Topical
Fluid mechanics, Physics, Radiation, Nuclear physics
Description
With the new NASA directive of returning to the Moon in 2024 as a stepping stone to missions to Mars and beyond, there is a renewed interest in developing nuclear thermal rockets (NTR) to reduce trip times. This thesis will focus on the analysis o...
DYNAMIC WATER SORPTION IN TREHALOSE-SALT MIXTURES: EFFECT OF COMPOSITION ON RETENTION OF THE AMORPHOUS STATE
Title
DYNAMIC WATER SORPTION IN TREHALOSE-SALT MIXTURES: EFFECT OF COMPOSITION ON RETENTION OF THE AMORPHOUS STATE
Author
Bagheri, Babak
Date Created
2014
Subjects--Topical
Mechanical engineering, Biomechanics
Description
The disaccharide trehalose has received considerable attention in the bio-preservation field due to its outstanding properties as a glass former, and it is widely used in the pharmaceutical and food industries to stabilize dried products. In part,...
Elucidating Dynamic Mechanisms for Extended Spectrum Antibiotic Resistance in Class A Beta-Lactamase through Machine Learning on Molecular Dynamics Simulations
Title
Elucidating Dynamic Mechanisms for Extended Spectrum Antibiotic Resistance in Class A Beta-Lactamase through Machine Learning on Molecular Dynamics Simulations
Author
Avery, Christopher
Date Created
2019
Subjects--Topical
Biophysics, Physics
Description
Beta-lactamase is a protein which is produced in bacteria and is a primary cause of antibiotic resistance to Beta Lactam antibiotics. Beta Lactams are among the most common types of antibiotics (including penicillin) and thus understanding the res...
Extending Topological Constraint Theory to Glass Networks with Hydrogen Bonding
Title
Extending Topological Constraint Theory to Glass Networks with Hydrogen Bonding
Author
Bloom, Austin
Date Created
2023
Subjects--Topical
Physics, Condensed matter
Description
Topological constraint theory has been successful in providing a simple model forthe liquid-glass transition in covalent bond bending networks. However, it is lim- ited to networks where all bonds are quenched and possess equivalent potential well...
Molecular clustering characteristics in ternary trehalose and choline dihydrogen phosphate solutions
Title
Molecular clustering characteristics in ternary trehalose and choline dihydrogen phosphate solutions
Author
Nikulsin, Nikita
Date Created
2018
Subjects--Topical
Physics
Description
Spatial and temporal characteristics of molecular structure in ternary solutions of trehalose and choline dihydrogen phosphate (CDHP) are studied using molecular dynamics simulations at 300 K for a range of solute concentrations with a 2:1 stoichi...
Quantifying the Binding Affinities of the PAI-H19Y Mutant of Sleeping Beauty Transposase to DNA
Title
Quantifying the Binding Affinities of the PAI-H19Y Mutant of Sleeping Beauty Transposase to DNA
Author
Arango, Maria
Date Created
2022
Subjects--Topical
Physics
Description
The Sleeping Beauty (SB) transposon system is the leading and only DNA transposon-based gene-delivery vehicle that has been adapted for human gene therapy. The SB system consists of a transposon DNA flanked by inverted terminal repeats (ITRs) and ...
Vascular Function in Patients With Chronic Ankle Instability and Healthy Adults
Title
Vascular Function in Patients With Chronic Ankle Instability and Healthy Adults
Author
Bruce, Casey
Date Created
2018
Subjects--Topical
Physiology, Neurosciences
Description
CASEY BRUCE. Vascular function in patients with chronic ankle instability and healthy adults. (Under the direction of DR. ABBEY THOMAS FENWICK)Introduction: Patients with CAI display impaired sensorimotor output and deficits in afferent/sensory pr...
Volume Microenvironment Self-Consistent Constraint Theory Applied to Protein Stability Prediction
Title
Volume Microenvironment Self-Consistent Constraint Theory Applied to Protein Stability Prediction
Author
Johannessen, Nicholas
Date Created
2021
Subjects--Topical
Biophysics, Physics
Description
Controlling thermodynamic stability is a challenge in protein engineering. Engineering a protein by introducing mutations into its sequence to increase efficacy can destabilize the protein thermodynamically, preventing it from functioning in its i...