Search results
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Title
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Evolution and dynamics of transcriptional regulation in bacteria
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Author
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Li, Shan
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Date Created
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2013
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Subjects--Topical
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Computer science, Statistics, Bioinformatics
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Description
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Although transcription is one of the most important biological functions of cells, our understanding of its regulation is still limited. In this dissertation, we have studied the transcriptional regulation in prokaryotes in three aspects. First, w...
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Title
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High Order H(div) Discontinuous Galerkin Methods for MHD Equations
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Author
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Wu, Jian
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Date Created
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2016
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Subjects--Topical
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Mathematics
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Description
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In this dissertation, we investigate the divergence-free discontinuous Galerkin method using the $\mathcal{H}$(\textbf{div}) basis, to solve the nonlinear ideal magnetohydrodynamics (MHD) equations. This is a novel approach to ensure the divergenc...
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Title
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Prediction of Cis-regulatory Modules in Genomes
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Author
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Ni, Pengyu
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Date Created
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2020
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Subjects--Topical
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Bioinformatics
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Description
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Annotating all cis-regulatory modules (CRMs) and constituent transcription factor (TF) binding sites (TFBSs) in genomes is essential to understand genome functions, however, the task remains highly challenging. In this dissertation, we first devel...
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Title
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THE ROLE OF XRCC1 AND POLYMERASE BETA IN GENOME INTEGRITY IN XENOPUS EGG EXTRACTS
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Author
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Cupello, Steven
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Date Created
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2019
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Subjects--Topical
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Molecular biology, Biology, Cytology
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Description
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Cells of organisms are constantly exposed to genomic insults such as oxidative stress from endogenous sources or environmental agents. Oxidative stress induces oxidative DNA damage such as apurinic/apyrimidinic (AP) sites, single-strand breaks (SS...
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Title
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USING BIOINFORMATICS TO ANALYZE THE ROLE OF MICROBIAL TAXA IN COMPLEX ECOSYSTEMS
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Author
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Sanapareddy, Nina
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Date Created
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2011
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Subjects--Topical
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Medicine, Bioinformatics, Information technology
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Description
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Microbes are abundant on earth and play a crucial role in the environment they inhabit. Before the dawn of metagenomics, the study of the effect of microorganisms on their environment was limited due to use of low throughput techniques that could ...