Search results | J. Murrey Atkins Library

Title: Assessments of Indel Annotation Programs and Comparative Somatic Indel Analysis in Cancer Genomes
Author: Chen, Jing
Date Created: 2020
Subjects--Topical: Bioinformatics
Description: Insertions and deletions (indels) represent the second largest variation type in human genomes and have been implicated in the development of cancer. Accurate indel annotation is of paramount importance in variants analysis in both healthy and dis...

Title: DE NOVO PREDICTION OF CIS-REGULATORY MODULES IN EUKARYOTIC ORGANISMS
Author: Niu, Meng
Date Created: 2014
Subjects--Topical: Bioinformatics
Description: Gene regulation networks (GRNs) are the bases for virtually all biological processes. To gain a global understanding of GRNs encoded in a genome, we first need to identify in all the cis-regulatory elements (CREs) recognized by transcription facto...

Title: INVESTIGATING THE GENETIC BASIS OF GENE EXPRESSION USING EQTL TECHNIQUES
Author: Quitadamo, Andrew
Date Created: 2018
Subjects--Topical: Bioinformatics
Description: With advances in genome sequencing technology, datasets with large sample sizes can be generated relatively quickly and cheaply, especially compared to the past decade or so. We can utilize this data to analyze the associations between genetic var...

Title: Mechanisms of acclimation and adaptation in the sea urchin Echinometra sp. EZ
Author: Ketchum, Remi
Date Created: 2017
Subjects--Topical: Biology
Description: Climate change has resulted in warming of coastal aquatic habitats around the world at almost every latitude, threatening ecosystems with a significant loss in biodiversity and occurring at a rate that may exceed species’ ability to adapt. Underst...

Title: Prevalence of Plasmodium vivax in Duffy-Negative Individuals Across Broad Regions of Ethiopia
Author: Little, Ebony
Date Created: 2023
Subjects--Topical: Biology
Description: Plasmodium parasites replicate asexually in the human host, and, in each replication cycle, a portion of the asexual stages develops into sexual gametocytes. The proportion of infections that carries gametocytes is a proxy for human-to-mosquito tr...

Title: The evolution of flavonoid pathway in legumes
Author: Safari, Sajedeh
Date Created: 2016
Subjects--Topical: Bioinformatics
Description: Considering the ever growing world population as well as climate change, it has become essential to improve crops in order to reach higher yields, more tolerance to pests and droughts, and better adaptation to different environments. The advanceme...

Title: Toward understanding protein-DNA interactions
Author: Lin, Maoxuan
Date Created: 2020
Subjects--Topical: Biology, Bioinformatics, Biochemistry
Description: Knowledge of protein-DNA interactions has important implications in understandingbiological activities and developing therapeutic drugs. Two types of protein-DNAinteractions exist: (1) interactions between double-stranded DNA-binding proteins(DSBs...

Title: UNDERSTANDING GENOME-WIDE GENE REGULATION IN PROKARYOTES USING OMICS DATA
Author: Seyedi Tabari, Seyed Ehsan
Date Created: 2016
Subjects--Topical: Bioinformatics, Information science, Biometry
Description: Gene annotation is a critical step for understanding functions of genomes and host organisms. However, accurately annotating thousands of sequenced genomes can be a challenging task. Further, although gene transcriptional regulation is crucial for...

Title: Understanding gene transcriptional regulation at single cell resolution
Author: Xu, Chen
Date Created: 2015
Subjects--Topical: Bioinformatics
Description: The recent advance of single-cell technologies has provided an unprecedented opportunity to bring new insights into many complex biological phenomena, such as the regulation of cell differentiation in a multi-cellular organism and cell-to-cell var...