Search results | J. Murrey Atkins Library

Title: ALGORITHMS FOR STRUCTURE BASED-PREDICTION OF TRANSCRIPTION FACTOR BINDING SITES
Author: Farrel, Alvin
Date Created: 2016
Subjects--Topical: Computer science, Biology, Bioinformatics
Description: Transcription factors (TFs) regulate gene expression through binding to specific target DNA sites. Accurate annotation of transcription factor binding sites (TFBSs) at genome scale represents an essential step toward our understanding of gene regu...

Title: An Integrated Phylogeographic Analysis of the Bantu Migration
Author: Ford, Colby
Date Created: 2018
Subjects--Topical: Computer science, Mathematics, Genetics
Description: "Bantu" is a term used to describe lineages of people in around 600 different ethnic groups on the African continent ranging from modern-day Cameroon to South Africa. The migration of the Bantu people, which occurred around 3,000 years ago, was in...

Title: Arboviruses: The hidden path of an imminent threat
Author: de Bernardi Schneider, Adriano
Date Created: 2018
Subjects--Topical: Virology, Bioinformatics, Epidemiology
Description: Arboviruses are a grade of viruses carried by arthropods, which have been in the headlines due to recent epidemics. Members of this grade are the families Flaviviridae which includes Zika (ZIKV), Dengue (DENV), Yellow Fever (YFV), among other viru...

Title: Assessments of Indel Annotation Programs and Comparative Somatic Indel Analysis in Cancer Genomes
Author: Chen, Jing
Date Created: 2020
Subjects--Topical: Bioinformatics
Description: Insertions and deletions (indels) represent the second largest variation type in human genomes and have been implicated in the development of cancer. Accurate indel annotation is of paramount importance in variants analysis in both healthy and dis...

Title: Echinoderm Transcriptomics
Author: Linchangco, Gregorio
Date Created: 2018
Subjects--Topical: Bioinformatics
Description: Tissue regeneration and biomineralization are expressed to a diverse extent across metazoans and their life stages. The potential for repair and regrowth in adult stages varies widely within phyla, class and species. For instance, few adult human ...

Title: Interactive Mining for Large-scale Neuro-Morphological Datasets
Author: Li, Zhongyu
Date Created: 2018
Subjects--Topical: Computer science, Neurosciences, Biomedical engineering
Description: In this dissertation, we aim to investigate advanced methods for the computational analytics of large-scale neuro-morphological datasets, which can help neuroscientists interactively explore neurons in real-time. Particularly, we tackle the neuro-...

Title: MECHANICAL BUCKLING OF INDIVIDUAL SILICON NANORIBBONS ON A COMPLIANT SUBSTRATE
Author: Chang, Siang Yee
Date Created: 2017
Subjects--Topical: Materials science
Description: About a decade ago, mechanical buckling evolves as a promising metrology to rapidly measure the elastic moduli of thin films and one-dimensional (1D) nanostructures. This form of metrology translates the geometrical measurements of the buckling pr...

Title: Next-Generation Sequencing Based Quantification of Microbial Communities and Gene Pathways
Author: Jones, Roshonda
Date Created: 2016
Subjects--Topical: Bioinformatics
Description: Humans act as a host to trillions of microorganisms. The collective of these microorganisms is called a host’s microbiota. There is a growing interest in the bacterial composition of the gut microbiome of humans (structure) and the role of the mic...

Title: Prediction of Cis-regulatory Modules in Genomes
Author: Ni, Pengyu
Date Created: 2020
Subjects--Topical: Bioinformatics
Description: Annotating all cis-regulatory modules (CRMs) and constituent transcription factor (TF) binding sites (TFBSs) in genomes is essential to understand genome functions, however, the task remains highly challenging. In this dissertation, we first devel...

Title: The Microbiota Multiverse: From Gut to Brain and Beyond
Author: Brown, Matthew
Date Created: 2019
Subjects--Topical: Microbiology, Bioinformatics
Description: This work explores the microbiomes of diverse biological contexts with various stakeholders and collaborators. It consists of six objectives: the first two relate to interaction between the gut microbiome and host health, the second two investigat...

Title: The Semantics of Diet and Health: Knowledge Based Discovery Through Data Integration, Text Mining, and Network Analysis
Author: Linchangco, Richard
Date Created: 2018
Subjects--Topical: Bioinformatics
Description: Consumption of fruits and vegetables has been linked to a reduced risk of cancer and other chronic diseases, but the molecular mechanisms supporting these connections remain largely unknown. A wealth of association data linking components of a pla...

Title: Towards large-scale and fine-grained image recognition
Author: Zhang, Xiaofan
Date Created: 2017
Subjects--Topical: Computer science
Description: In this dissertation, we aim to investigate the problem of large-scale and fine-grained image recognition, which focuses on the differentiation of subtle differences among subordinate classes and a large number of images. Particularly, we tackle t...

Title: UNDERSTANDING BIAS IN NEXT-GENERATION SEQUENCING TECHNOLOGIES AND ANALYSES
Author: Price, Adam
Date Created: 2017
Subjects--Topical: Biology, Bioinformatics, Biophysics
Description: The problem of bias resulting from biological and technological sources is one that must be consistently reexamined alongside the development of new technologies and methods of analysis. This dissertation addresses the complexities of bias identif...

Title: UNDERSTANDING GENOME-WIDE GENE REGULATION IN PROKARYOTES USING OMICS DATA
Author: Seyedi Tabari, Seyed Ehsan
Date Created: 2016
Subjects--Topical: Bioinformatics, Information science, Biometry
Description: Gene annotation is a critical step for understanding functions of genomes and host organisms. However, accurately annotating thousands of sequenced genomes can be a challenging task. Further, although gene transcriptional regulation is crucial for...