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FACTORS SHED BY BREAST TUMOR CELLS, TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME ACTIVITIES, AND THE GENERATION OF PRO-TUMOR MACROPHAGES
Title
FACTORS SHED BY BREAST TUMOR CELLS, TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME ACTIVITIES, AND THE GENERATION OF PRO-TUMOR MACROPHAGES
Author
Rego, Stephen
Date Created
2013
Subjects--Topical
Biology
Description
The role of the tumor microenvironment, especially of tumor associated macrophages (TAMs), in the progression and metastatic spread of breast cancer is well established. TAMs are activated in the breast tumor microenvironment to express primarily ...
HOST FACTORS CONTROLLING VIRUS INFECTION: IMPLICATIONS FOR ANTIVIRALS AND VIROTHERAPY
Title
HOST FACTORS CONTROLLING VIRUS INFECTION: IMPLICATIONS FOR ANTIVIRALS AND VIROTHERAPY
Author
Shah, Nirav
Date Created
2013
Subjects--Topical
Virology, Oncology
Description
Viruses are obligate intracellular parasites rely heavily on host components and pathways for their replication. Studying different cellular factors affecting viral infection can enable us to identify novel drug targets, improve current antiviral ...
NOVEL ROLES OF MICRORNAS IN HEPATITIS C
Title
NOVEL ROLES OF MICRORNAS IN HEPATITIS C
Author
Sendi, Hossein
Date Created
2013
Subjects--Topical
Virology, Biology
Description
Approximately, 170 million people are infected by hepatitis C virus (HCV) worldwide, and of these, nearly 85% will develop chronic hepatitis C (CHC). Despite finding new anti-viral treatment that increase response rate from 45 % to 65-70 %, invest...
Topoisomerase II Inhibitors Induce an Illegitimate Genome Rearrangement Common in Infant Leukemia
Title
Topoisomerase II Inhibitors Induce an Illegitimate Genome Rearrangement Common in Infant Leukemia
Author
Bariar, Bhawana
Date Created
2013
Subjects--Topical
Molecular biology
Description
Infant acute leukemias account for ~30% of all malignancy seen in childhood across the Western world. They are aggressive and characterized by rapid onset shortly after birth. The majority of these have rearrangements involving the MLL (mixed line...