Search results | J. Murrey Atkins Library

Title: EFFECTS OF SILIBININ ON ETHANOL-MEDIATED HEPATOCELLULAR CARCINOMA PROGRESSION IN MALE AND FEMALE MICE
Author: Warner, Elizabeth
Date Created: 2011
Subjects--Topical: Biology
Description: Ethanol is a significant risk for the development of hepatic cirrhosis and progression to hepatocellular carcinoma (HCC). While females are more susceptible to the deleterious effects of ethanol, the incidence of cirrhosis and HCC is significantly...

Title: EXPERIMENTAL AND COMPUTATIONAL STRATEGIES FOR ENHANCING MASS TRANSPORT AND CRYOPRESERVATION OF BIOLOGICAL TISSUES
Author: Karthik Kumar, Balasubramanian
Date Created: 2012
Subjects--Topical: Mechanical engineering, Biomedical engineering
Description: A bioreactor is a large-scale engineered in vitro device that maintains a 3D arrangement of functioning cells for use in various bioengineering applications. The current work is focused on heat and mass transfer issues related to the bioreactor's ...

Title: IDENTIFICATION OF EPITHELIAL OVARIAN TUMOR SPECIFIC APTAMERS THAT BIND AND INTERNALIZE INTO TARGET CELLS
Author: Benedetto, Gregory
Date Created: 2015
Subjects--Topical: Chemistry, Biology
Description: New clinical tools that aid in the early diagnosis of ovarian malignancies will significantly help reduce mortality and improve current long-term survival rates. The objective of the work presented here was to identify ovarian tumor specific singl...

Title: Nonsegmented negative strand RNA viruses: viral RNA cap methylation and potential applications as an anticancer therapy
Author: Murphy, Andrea
Date Created: 2012
Subjects--Topical: Virology, Biology
Description: The viruses of the order Mononegavirales include important human, animal, and plant pathogens and additionally, have great potential as vaccine, oncolytic and gene therapy vectors. This dissertation focuses on two prototypic Mononegavirales, vesic...

Title: Production of Immunomodulatory Proteins in Glycine max for use in Diagnostics and as Therapeutics
Author: Powell, Rebecca
Date Created: 2010
Subjects--Topical: Molecular biology
Description: ABSTRACTREBECCA DIANE POWELL. Production of Immunomodulatory Proteins in Glycine max for Use in Diagnostics and as Therapeutics. (Under the direction of DR. KENNETH L. BOST) Immunomodulatory proteins can be utilized in diagnostic assays, as tolera...

Title: RANK-L expression in Staphylococcus aureus- induced osteomyelitis, therapeutic intervention using nanotechnology and use of UV-killed bacteria as an osteoconductive coating for biomaterials.
Author: Somayaji, Shankari
Date Created: 2009
Subjects--Topical: Microbiology
Description: Staphylococcus aureus is responsible for approximately 80% of all cases of human osteomyelitis. RANK-L is an essential signal produced by osteoblasts and is required for full osteoclastic differentiation. PGE₂ - induced bone resorption involves bo...

Title: ROLE OF AQUAPORINS DURING HEPATOCELLULAR CARCINOMA INITIATION AND PROGRESSION
Author: Mattocks, Matthew
Date Created: 2010
Subjects--Topical: Molecular biology, Cytology, Oncology
Description: Aquaporins (AQPs) are ubiquitously expressed proteinaceous water channels involved in numerous physiological processes including bile production and apoptosis. Aquaporins 8 and 9 are expressed in hepatocytes, and are down regulated in a rat model ...

Title: Regulation of Myosin IIIa Motor/Kinase Activity
Author: Moore, Judy
Date Created: 2009
Subjects--Topical: Biochemistry, Neurosciences, Cytology
Description: Myosin IIIa, a motor protein that localizes to actin-rich regions of photoreceptors and to stereocilia of inner ear hair cells, is associated with the hearing process in vertebrates and with phototransduction for invertebrates. It contains a large...

Title: The role of the dopaminergic system in the regulation of physical activity in mice
Author: Knab, Amy
Date Created: 2009
Subjects--Topical: Molecular biology, Genetics, Physiology
Description: Physical activity (PA) is important to human health, and the genetic and biological regulating factors of physical activity are only beginning to be understood. The dopamine (DA) system has been shown to regulate motivation, and locomotor behavior...