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Dissecting functional differences in Hsp70 isoforms in nematostella vectensis
Title
Dissecting functional differences in Hsp70 isoforms in nematostella vectensis
Author
Waller, Shawn
Date Created
2018
Subjects--Topical
Molecular biology
Description
Heat shock protein 70s (Hsp70s) are a highly conserved class of molecular chaperones that are involved in cellular processes in all organisms such as stress response, homeostatic maintenance, and cell cycle progression. The organism Nematostella v...
Inflammasome-driven IL-1ß and IL-18 cytokine signaling between macrophages and cancer cells within the breast tumor microenvironment
Title
Inflammasome-driven IL-1ß and IL-18 cytokine signaling between macrophages and cancer cells within the breast tumor microenvironment
Author
Suryaprakash, Deepika
Date Created
2018
Subjects--Topical
Molecular biology, Oncology
Description
Breast cancer especially triple-negative breast cancer remains deadly, despite detection, monitoring and therapeutic advances. Indeed, aggressive breast cancers metastasize to tissues including the brain, bones, and lungs. Metastasis is favored by...
THE ROLE OF TRANSLESION SYNTHESIS POLYMERASES REV1 AND POL η IN DNA DAMAGE RESPONSE
Title
THE ROLE OF TRANSLESION SYNTHESIS POLYMERASES REV1 AND POL η IN DNA DAMAGE RESPONSE
Author
McLeod, Melissa
Date Created
2016
Subjects--Topical
Molecular biology, Biology, Cytology
Description
Our cells endure continuous challenges from byproducts of endogenous metabolic processes as well as outside sources such as UV light and environmental polltants. The DNA Damage Response (DDR) helps organisms cope with damage and coordinate an appr...
VPS501, A NOVEL SNX-BAR PROTEIN INVOLVED IN AUTOPHAGY
Title
VPS501, A NOVEL SNX-BAR PROTEIN INVOLVED IN AUTOPHAGY
Author
goyal, Shreya
Date Created
2021
Subjects--Topical
Biochemistry, Cytology, Molecular biology
Description
ABSTRACTCareful control of intracellular signaling pathways plays an important role in a cell’s ability to maintain stable internal conditions in the face of an ever-changing extracellular environment. This is particularly true as it relates to th...