Search results
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Title
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A NOVEL ANTIBODY FOR THE DETECTION AND TREATMENT OF PANCREATIC DUCTAL ADENOCARCINOMA
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Author
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Wu, Shuta
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Date Created
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2017
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Subjects--Topical
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Biology, Oncology
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Description
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Pancreatic ductal adenocarcinoma (PDA) remains the most aggressive cancer with a 5-year survival rate below 10%. Two of the major contributors to this dismal prognosis are late-stage diagnosis and limited treatment options. Common symptoms of PDA ...
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Title
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Analysis and Development of Targeting Strategies for Bacterial Sugars
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Author
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Erickson, Katelyn
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Date Created
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2018
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Subjects--Topical
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Chemistry, Biochemistry
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Description
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Bacterial cell surface exopolysaccharides aid in protecting microbes from the defense mechanisms of the host, and differ substantially in structure between species. Exploiting these structural differences would be advantageous to target certain ty...
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Title
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Long-term study of changes in microbiota in a Cystic Fibrosis patient
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Author
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Stokell, Joshua
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Date Created
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2013
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Subjects--Topical
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Biology, Microbiology
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Description
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Application of culture-independent techniques have revealed the presence of more types of bacteria than were previously thought, which led to the current description of Cystic Fibrosis (CF) being a polymicrobial disease. We know this polymicrobial...
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Title
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Synthesis, Characterization and Functionalization of Anti-Bisarene Scaffolds
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Author
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Franklin, Joseph
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Date Created
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2017
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Subjects--Topical
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Chemistry
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Description
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Since the advent of rational organic synthesis, practitioners in the field have been refining their craft to target compounds of immense complexity. Synthetic methodologies discovered through these pursuits have provided a fertile ground to expand...
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Title
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Synthesis, Characterization, and Reactivity of Cross-Conjugated Frameworks
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Author
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Hamilton, Victoria
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Date Created
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2018
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Subjects--Topical
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Chemistry, Chemistry, Organic
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Description
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ABSTRACTVICTORIA LEIGH HAMILTON. Synthesis, Characterization, and Reactivity of Cross-Conjugated Frameworks. (Under the direction of MARKUS ETZKORN)Molecules with cross-conjugated -systems possess unique structures and reactivity due to their dis...
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Title
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THE ROLE OF MUC1 IN REGULATION AND PROGRESSION OF CANCER
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Author
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Sahraeimanouchehrabadi, Mahnaz
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Date Created
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2011
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Subjects--Topical
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Immunology, Biology, Oncology
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Description
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MUC1 is a heavily glycosylated transmembrane glycoprotein which is overexpressed and aberrantly glycosylated in most human carcinomas. MUC1 contains a large tandem repeat, a short transmembrane, and a small cytoplasmic tail. Both tandem repeat and...